Estrogen receptor alpha (ERα) has been recognized now for several decades as playing a
key role in reproduction and exerting functions in numerous nonreproductive tissues. In this …

Reproduction is controlled by the hypothalamic-pituitary-gonadal (HPG) axis. Gonadotropin-
releasing hormone (GnRH) neurons play a central role in this axis through production of …

Neuropeptides are found in many mammalian CNS neurons where they play key roles in
modulating neuronal activity. In contrast to amino acid transmitter release at the synapse …

The concept that different systems control episodic and surge secretion of gonadotropin‐
releasing hormone (GnRH) was well established by the time that GnRH was identified and …

In women, the non-growing population of follicles that comprise the ovarian reserve is
determined at birth and serves as the reservoir for future fertility. This reserve of dormant …

This review aims at synthesizing the most relevant information regarding the
neuroendocrine circuits controlling reproduction, mainly gonadotropin release, in teleost …

Kisspeptin (a product of the Kiss1 gene) and its receptor (GPR54 or Kiss1r) have emerged
as key players in the regulation of reproduction. Mutations in humans or genetically targeted …

Estradiol is the most potent and ubiquitous member of a class of steroid hormones called
estrogens. Fetuses and newborns are exposed to estradiol derived from their mother, their …

Traditionally sex hormones have been associated with reproductive and developmental
processes only. Since the 1950s we know that hormones can have organizational effects on …

In November 1955, Geoffrey Harris published a paper based on the Christian A Herter
Lecture he had given earlier that year at Johns Hopkins University in Baltimore, MD, USA …