Myelofibrosis and survival prognostic models: a journey between past and future
A Duminuco, A Nardo, G Giuffrida, S Leotta… - Journal of Clinical …, 2023 - mdpi.com
Among the myeloproliferative diseases, myelofibrosis is a widely heterogeneous entity
characterized by a highly variable prognosis. In this context, several prognostic models have …
characterized by a highly variable prognosis. In this context, several prognostic models have …
Hemostasis and complement in allogeneic hematopoietic stem cell transplantation: clinical significance of two interactive systems
DA Tsakiris, E Gavriilaki, I Chanou… - Bone marrow …, 2024 - nature.com
Hematopoietic stem cell transplantation (HCT) represents a curative treatment option for
certain malignant and nonmalignant hematological diseases. Conditioning regimens before …
certain malignant and nonmalignant hematological diseases. Conditioning regimens before …
Biomarkers for early complications post hematopoietic cell transplantation: Insights and challenges
B Balakrishnan, UP Kulkarni, AA Pai… - Frontiers in …, 2023 - frontiersin.org
Hematopoietic cell transplantation is an established curative treatment option for various
hematological malignant, and non-malignant diseases. However, the success of HCT is still …
hematological malignant, and non-malignant diseases. However, the success of HCT is still …
The pharmacotherapeutic management of patients with myelofibrosis: looking beyond JAK inhibitors
A Duminuco, C Vetro, C Giallongo… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction The approach to myelofibrosis (MF) has been revolutionized in recent years,
overcoming the traditional therapies, often not very effective. Janus kinase inhibitors (JAKi …
overcoming the traditional therapies, often not very effective. Janus kinase inhibitors (JAKi …
Easix score correlates with endothelial dysfunction biomarkers and predicts risk of acute graft-versus-host disease after allogeneic transplantation
A Pedraza, MQ Salas, LG Rodríguez-Lobato… - … and Cellular Therapy, 2024 - Elsevier
Plasma biomarkers of endothelial dysfunction have been postulated for the diagnosis and
prognosis of acute graft-versus-host disease (aGVHD). However, their use is not validated in …
prognosis of acute graft-versus-host disease (aGVHD). However, their use is not validated in …
MASP2 inhibition by narsoplimab suppresses endotheliopathies characteristic of transplant-associated thrombotic microangiopathy: in vitro and ex vivo evidence
Transplant-associated thrombotic microangiopathy (TA-TMA) is an endotheliopathy
complicating up to 30% of allogeneic hematopoietic stem cell transplants (alloHSCT) …
complicating up to 30% of allogeneic hematopoietic stem cell transplants (alloHSCT) …
Diagnosis and management of endothelial disorders following haematopoietic stem cell transplantation
A McEwan, M Greenwood, C Ward… - Internal Medicine …, 2023 - Wiley Online Library
Haematopoietic stem cell transplantation is a mainstay of therapy for numerous malignant
and nonmalignant diseases. Endothelial activation and dysfunction occur after stem cell …
and nonmalignant diseases. Endothelial activation and dysfunction occur after stem cell …
[HTML][HTML] Incidence and role of recipient-specific antibodies in allogeneic hematopoietic cell transplantation from mismatched related donors
A Sadowska-Klasa, A Dukat-Mazurek… - … and Cellular Therapy, 2024 - Elsevier
High titer of donor-specific antibodies (DSAs) increases the risk of graft rejection after
mismatched related hematopoietic cell transplantation (HCT). There are no data regarding …
mismatched related hematopoietic cell transplantation (HCT). There are no data regarding …
Fetal liver CD34+ contain human immune and endothelial progenitors and mediate solid tumor rejection in NOG mice
T Celhar, X Li, Y Zhao, HC Tay, A Lee, HH Liew… - Stem Cell Research & …, 2024 - Springer
Background Transplantation of CD34+ hematopoietic stem and progenitor cells (HSPC) into
immunodeficient mice is an established method to generate humanized mice harbouring a …
immunodeficient mice is an established method to generate humanized mice harbouring a …
The function of the complement system remains fully intact throughout the course of allogeneic stem cell transplantation
B Fageräng, L Cyranka, C Schjalm… - Frontiers in …, 2024 - frontiersin.org
Introduction Hematopoietic stem cell transplantation (HSCT) is associated with immune
complications and endothelial dysfunction due to intricate donor-recipient interactions …
complications and endothelial dysfunction due to intricate donor-recipient interactions …