Effect of COVID-19 pandemic on patients who have undergone liver transplantation: Retrospective cohort study
Background: In liver transplant (LT) recipients, immunosuppressive therapy may potentially
increase the risk of severe COVID-19 and may increase the mortality in patients. However …
increase the risk of severe COVID-19 and may increase the mortality in patients. However …
Endocrine therapy and strategies to overcome therapeutic resistance in breast cancer
MR Mancuso, SA Massarweh - Current problems in cancer, 2016 - Elsevier
Despite the remarkable success of endocrine therapy in the treatment of patients with
estrogen receptor (ER)-positive breast cancer, not all patients derive benefit from such …
estrogen receptor (ER)-positive breast cancer, not all patients derive benefit from such …
Therapeutic resistance in acute myeloid leukemia cells is mediated by a novel ATM/mTOR pathway regulating oxidative phosphorylation
HJ Park, MA Gregory, V Zaberezhnyy, A Goodspeed… - Elife, 2022 - elifesciences.org
While leukemic cells are susceptible to various therapeutic insults, residence in the bone
marrow microenvironment typically confers protection from a wide range of drugs. Thus …
marrow microenvironment typically confers protection from a wide range of drugs. Thus …
Pan-European expert meeting on the use of metronomic chemotherapy in advanced breast cancer patients: the PENELOPE project
Introduction Metronomic chemotherapy (mCHT) is a treatment regimen in which drugs are
administered frequently or continuously and that maintains low, prolonged, and …
administered frequently or continuously and that maintains low, prolonged, and …
The immune system as a chronotoxicity target of the anticancer mTOR inhibitor everolimus
The circadian timing system controls many biological functions in mammals including
xenobiotic metabolism, detoxification, cell proliferation, apoptosis and immune functions …
xenobiotic metabolism, detoxification, cell proliferation, apoptosis and immune functions …
Positive effects on hematological and biochemical imbalances in patients with metastatic breast cancer stage IV, of BP-C1, a new anticancer substance
S Lindkær-Jensen, S Larsen… - Drug Design …, 2015 - Taylor & Francis
A benzene-poly-carboxylic acid complex with cis-diammineplatinum (II) dihydrocholride, BP-
C1 is currently used in clinical trials in treating metastatic breast cancer. BP-C1 controls …
C1 is currently used in clinical trials in treating metastatic breast cancer. BP-C1 controls …
[HTML][HTML] Recommendations for the management of renal involvement in tuberous sclerosis complex
G Ariceta, MJ Buj, M Furlano, V Martínez… - Nefrología (English …, 2020 - Elsevier
Tuberous sclerosis complex (TSC) is a rare, hereditary, multisystemic disease with a broad
phenotypic spectrum. Its management requires the collaboration of multiple specialists. Just …
phenotypic spectrum. Its management requires the collaboration of multiple specialists. Just …
Toxicity of a combined therapy using the mTOR-inhibitor everolimus and PRRT with [177Lu]Lu-DOTA-TATE in Lewis rats
J Zellmer, HY Yen, L Kaiser, E Mille, FJ Gildehaus… - EJNMMI research, 2020 - Springer
Purpose Peptide receptor radionuclide therapy (PRRT) with [177 Lu] Lu-DOTA 0, TYR 3-
octreotate ([177 Lu] Lu-DOTA-TATE) and the mechanistic target of rapamycin (mTOR) …
octreotate ([177 Lu] Lu-DOTA-TATE) and the mechanistic target of rapamycin (mTOR) …
Managing the oncologic patient with suspected pneumonia in the intensive care unit
D Leoni, B Encina, J Rello - Expert Review of Anti-infective …, 2016 - Taylor & Francis
Introduction: Solid cancer patients are frequently admitted in intensive care units for critical
events. Improving survival rates in this setting is considered an achievable goal today …
events. Improving survival rates in this setting is considered an achievable goal today …
Risk of anemia attributable to everolimus in patients with cancer: a meta-analysis of randomized controlled trials
Background: Everolimus, an inhibitor of mammalian target of rapamycin (mTOR) used for the
treatment of various solid tumors, is associated with anemia, which can lead to morbidity and …
treatment of various solid tumors, is associated with anemia, which can lead to morbidity and …