Cryptococcus neoformans é o agente etiológico da criptococose, enfermidade que afeta
principalmente pacientes imunocomprometidos e causa aproximadamente 180.000 óbitos …

Cryptococcus neoformans is a pathogenic yeast which causes cryptococcal meningitis in
immunocompromised patients, causing heterogeneous infection outcomes in both HIV …

The efficacy of recombinant interferon γ (rIFN-γ) for cryptococcal meningoencephalitis has
been poorly understood. Compared to Cryptococcus gattii, rIFN-γ significantly improved the …

4.4 Indirekte Antikörpereffekte __________________________________… 50 4.4. 1
Venetoclax in Kombination mit therapeutischen Antikörpern führt zu keiner Erhöhung der …

Cryptococcus neoformans is an opportunistic pathogen and a leading cause of life‑
threatening fungal infections in the immunocompromised. Individuals that are at greater risk …

Many microbial pathogens are able to evade killing by phagocytes of the innate immune
system. This thesis focuses on two pathogens: the fungal pathogen\(Cryptococcus\) …

Toll-like receptors (TLRs) play critical roles in human innate and adaptive immune
responses and although they are well characterized, there remain gaps in our …

Cryptococcus has a polysaccharide capsule, which is the major virulence factor of the
organism. This chapter covers the interactions of Cryptococcus with immune cells, with a …

Cryptoccosis remains the leading cause of fungal meningitis worldwide. Whilst one of the
causative agents, C. neoformans has been described as an opportunistic pathogen of the …

Cryptococcus neoformans is an encapsulated yeast that causes cryptococcosis, a life-
threatening disease that develops following inhalation and dissemination of the ubiquitous …