Although tuberculosis is largely a curable disease, it remains a major cause of morbidity and
mortality worldwide. Although the standard 6-month treatment regimen is highly effective for …

Background: Mobile health (mHealth) is a rapidly emerging market, which has been
implemented in a variety of different disease areas. Tuberculosis remains one of the most …

Objectives Concomitant food intake influences pharmacokinetics of first-line anti-TB drugs in
healthy volunteers. However, in treatment-naive TB patients who are starting with drug …

Variable pharmacokinetics of rifampin in tuberculosis (TB) treatment can lead to poor
outcomes. Urine spectrophotometry is simpler and more accessible than recommended …

Abstract Background and Objective Quantifying exposure to drugs for personalized dose
adjustment is of critical importance in patients with tuberculosis who may be at risk of …

Background Tuberculosis remains the major public health problem besides tremendous
efforts to combat it. Most tuberculosis patients are treated with a standard dose of first-line …

Background. The hollow fiber system model of tuberculosis (HFS-TB) is designed to perform
pharmacokinetics/pharmacodynamics (PK/PD) experiments, and hence the design of …

Introduction: Tuberculosis (TB) remains the leading cause of death from a curable infectious
disease; drug-resistant TB threatens to dismantle all prior gains in global control. Suboptimal …

Purpose This systematic review and meta-analysis assesses the pharmacokinetic (PK)
summary estimates of isoniazid (INH) between healthy volunteers and patients with …

Mycobacterium abscessus causes chronic pulmonary infections that are extremely difficult to
cure. The currently recommended combination therapy is associated with high failure rates …