Today, dendrimers are the main nanoparticle applied to drug delivery systems. The
physicochemical characteristics of dendrimers and their versatility structural modification …

Hepatocellular carcinoma (HCC) is one of the most common malignant tumors worldwide,
with high rates of recurrence and death. Surgical resection and ablation therapy have limited …

Abstract Background MiR-199a-3p (miR-199a) can enhance the chemosensitivity of
hepatocellular carcinoma (HCC). Because of the easy degradation of miRNA by direct …

Hepatocellular carcinoma (HCC) is one of the deadliest cancers due to its complexities,
reoccurrence after surgical resection, metastasis and heterogeneity. In addition to sorafenib …

A successful drug delivery to a specific site relies on two essential factors including; efficient
entrapment of the drug within the carrier and successful delivery of drug-loaded nanocarrier …

The specific-targeting approach could promote the specificity of diagnosis and the accuracy
of cancer treatment. The choice of a specific-targeting receptor is the key step in this …

Background The main objective of this study was to develop novel BSA nanoparticles (BSA
NPs) for improving the bioavailability of curcumin as an anticancer drug, and those BSA NPs …

Combination of both internal-and external-stimuli responsive strategies in nanoplatforms
can maximize therapeutic outcomes by overcoming drug efflux-mediated resistance and …

The development of nanostructures for therapeutic purpose is rapidly growing, following the
results obtained in vivo in animal models and in the clinical trials. Unfortunately, the potential …

The effectiveness of chemotherapy in hepatocellular carcinoma (HCC) is restricted by
chemo-resistance and systemic side effects. To improve the efficacy and safety of …