[PDF][PDF] 青蒿素与疟疾: 药物激活, 作用机理及抗药性的研究进展

苏新专, 李剑 - 科学通报, 2017 - core.ac.uk
摘要如能及早确诊并合理救治, 疟疾是可以通过抗疟药来治愈的. 然而, 抗药性疟原虫通常在一种
新型药物的大规模使用后的数年内就会出现. 随着疟原虫几乎对所有类型的抗疟药均产生了不同 …

[PDF][PDF] Artemisinin alleviates pentylenetetrazole-induced kindling in male mice: involvement of gephyrin targeting.

AM Al-Humaidhi, AH Abd, HF Ghazi - EurAsian Journal of …, 2020 - researchgate.net
Background: Epilepsy is a common brain disorder that is not quite controlled via available
antiepileptic drugs. Gephyrin is a scaffolding protein that interacts particularly with GABAA …

[PDF][PDF] Characterization of Plasmodium falciparum Pantothenate Kinase and Identification of Its Inhibitors From Natural Products

T Sakura, DK Inaoka, K Shiomi, T Nozaki - academia.edu
Coenzyme A (CoA) is a well-known cofactor that plays an essential role in many metabolic
reactions in all organisms. In Plasmodium falciparum, the most deadly among Plasmodium …

Mechanistic and Structural Insights into Oxidative Stress in Malaria and Anti-malarial Drug Metabolism

V Sharma, S Singh - Oxidative Stress in Microbial Diseases, 2019 - Springer
Malaria is a devastating infectious disease affecting mostly tropical and sub-tropical regions.
Owning to the emergence of resistance to the existing chemotherapy, the development of …

Development and validation of a generic method for determination of antimalarial drugs using high-performance thin-layer chromatography (HPTLC)

GGN Mekah, JM Kakumba, DI Kitenge, GD Bujo… - 2023 - researchsquare.com
Development and validation of a generic method for determination of antimalarial drugs using
high- performance thin-layer chroma Page 1 Page 1/19 Development and validation of a …

Hepatitis y embarazo

G Ducarme, M Schnee, V Dochez - EMC-Ginecología-Obstetricia, 2016 - Elsevier
En la mujer en edad de procrear, dos tercios de las hepatopatías se relacionan con el
embarazo. En general, la gravedad y la frecuencia de las hepatitis virales son idénticas a …

Tgf-beta inhibition, agents and composition therefor

V Trieu - 2021 - Google Patents
ZRKFYGHZFMAOKI-QMGMOQQFSA-N Tgfbeta Chemical compound C ([C@ H](NC (=
O)[C@ H](C (C) C) NC (= O) CNC (= O)[C@ H](CCC (O)= O) NC (= O)[C@ H](CCCNC (N) …

Exploring nanotechnologies for the effective therapy of malaria using plant-based medicines

EF Oga, KK Singh - Current Pharmaceutical Design, 2016 - ingentaconnect.com
Malaria is a potentially lethal disease caused by species of the plasmodium parasite.
Despite the advances in the interventions for its control and approaches to manage fatality …

A Review on Antibiotic Resistance in Microorganisms

YA Jassim - Biomedicine and Chemical Sciences, 2022 - journals.irapa.org
1Antibiotics are medicines used to prevent and treat bacterial infections. Antibiotic
resistance occurs when bacteria change themselves in response to the use of these …

[PDF][PDF] Research Article Effect of Allicin and Artesunate Combination Treatment on Experimental Mice Infected with Plasmodium berghei

S Ounjaijean, V Somsak - 2022 - academia.edu
Malaria is still a significant health problem in endemic countries and increases Plasmodium
resistance to the available antimalarial drugs. Hence, this study aimed to investigate the …