Recent perspectives in ocular drug delivery
R Gaudana, J Jwala, SHS Boddu, AK Mitra - Pharmaceutical research, 2009 - Springer
Anatomy and physiology of the eye makes it a highly protected organ. Designing an effective
therapy for ocular diseases, especially for the posterior segment, has been considered as a …
therapy for ocular diseases, especially for the posterior segment, has been considered as a …
A review of nanocarrier-mediated drug delivery systems for posterior segment eye disease: Challenges analysis and recent advances
R Wang, Y Gao, A Liu, G Zhai - Journal of drug targeting, 2021 - Taylor & Francis
Posterior segment eye disease is a leading cause of irreversible vision impairment and
blindness. As the unique organ for vision, eyes are protected by various protective barriers …
blindness. As the unique organ for vision, eyes are protected by various protective barriers …
Pharmaceutical preformulation and formulation
M Gibson - Drugs Pharm Sci, 2001 - api.taylorfrancis.com
The first edition of this book published in 2001 has been more successful than I ever
imagined, as indicated by the excellent reviews it has received, the continued demand, and …
imagined, as indicated by the excellent reviews it has received, the continued demand, and …
Protein and polypeptide mediated delivery to the eye
SA Attia, JA MacKay - Advanced drug delivery reviews, 2022 - Elsevier
Hybrid or recombinant protein-polymers, peptide-based biomaterials, and antibody-targeted
therapeutics are widely explored for various ocular conditions and vision correction. They …
therapeutics are widely explored for various ocular conditions and vision correction. They …
Codrug: An efficient approach for drug optimization
Codrug or mutual prodrug is an approach where various effective drugs, which are
associated with some drawbacks, can be modified by attaching with other drugs of same or …
associated with some drawbacks, can be modified by attaching with other drugs of same or …
From the cover: zebrafish larvae are insensitive to stimulation by cocaine: importance of exposure route and toxicokinetics
Zebrafish (Danio rerio) larvae have been suggested as vertebrate model to complement or
even replace mammals for rapidly assessing behavioral effects of psychoactive drugs. Yet …
even replace mammals for rapidly assessing behavioral effects of psychoactive drugs. Yet …
Antioxidant defense and pseudoexfoliation syndrome: an updated review
S Mastronikolis, K Kagkelaris, M Pagkalou… - Medical …, 2022 - mdpi.com
Oxidative stress (OS) affects the anterior ocular tissues, rendering them susceptible to
several eye diseases. On the other hand, protection of the eye from harmful factors is …
several eye diseases. On the other hand, protection of the eye from harmful factors is …
Fluorescent nanosystems for drug tracking and theranostics: Recent applications in the ocular field
E Zingale, A Romeo, S Rizzo, C Cimino, A Bonaccorso… - Pharmaceutics, 2022 - mdpi.com
The greatest challenge associated with topical drug delivery for the treatment of diseases
affecting the posterior segment of the eye is to overcome the poor bioavailability of the …
affecting the posterior segment of the eye is to overcome the poor bioavailability of the …
Activity and expression of carboxylesterases and arylacetamide deacetylase in human ocular tissues
As a multitissue organ, the eye possesses unique anatomy and physiology, including
differential expression of drug-metabolizing enzymes. Several hydrolytic enzymes that play …
differential expression of drug-metabolizing enzymes. Several hydrolytic enzymes that play …
The codrug approach for facilitating drug delivery and bioactivity
IA Aljuffali, CF Lin, CH Chen… - Expert opinion on drug …, 2016 - Taylor & Francis
Introduction: Codrug or mutual prodrug is a drug design approach to chemically bind two or
more drugs to improve therapeutic efficiency or decrease adverse effects. The codrug can …
more drugs to improve therapeutic efficiency or decrease adverse effects. The codrug can …