Components used in plastics, such as phthalates, bisphenol A (BPA), polybrominated
diphenyl ethers (PBDE) and tetrabromobisphenol A (TBBPA), are detected in humans. In …

As a multifunctional cytokine, tumor necrosis factor alpha (TNF‐α) exerts a series of
biological actions in different cells, tissues, organs, and species and has been demonstrated …

Aim: Adipokines are protein products of adipose tissue with paracrine and endocrine
actions, which have been implicated in the pathogenesis of cardiovascular disease. Locally …

Parkinson's disease (PD) exhibits systemic effects on the human metabolism, with emerging
roles for the gut microbiome. Here, we integrate longitudinal metabolome data from 30 drug …

Abstract Background In patients with Normal Glucose Tolerance (NGT) some causes of
ischemic heart disease (IHD) were not completely investigated. The role both of metabolic …

RA is characterized by a systemic inflammatory state, in which immune cells and soluble
mediators play a crucial role. These inflammatory processes resemble those in other chronic …

Objective: Atherosclerosis is a complex process characterized by an increase in vascular
wall thickness owing to the accumulation of cells and extracellular matrix between the …

Mitochondria play important roles in human physiological processes, and therefore, their
dysfunction can lead to a constellation of metabolic and nonmetabolic abnormalities such as …

Obesity is the cause of a large proportion of breast cancer incidences and mortality in post-
menopausal women. In obese people, elevated levels of various growth factors such as …

Central obesity is a relevant risk factor for major cardiovascular events due to the
atherosclerotic involvement of coronary, cerebral and lower limb arterial vessels. A major …