Roles of transposable elements in the regulation of mammalian transcription
Transposable elements (TEs) comprise about half of the mammalian genome. TEs often
contain sequences capable of recruiting the host transcription machinery, which they use to …
contain sequences capable of recruiting the host transcription machinery, which they use to …
Is plasticity of synapses the mechanism of long-term memory storage?
WC Abraham, OD Jones, DL Glanzman - NPJ science of learning, 2019 - nature.com
It has been 70 years since Donald Hebb published his formalized theory of synaptic
adaptation during learning. Hebb's seminal work foreshadowed some of the great …
adaptation during learning. Hebb's seminal work foreshadowed some of the great …
[HTML][HTML] Biomarkers of nutrition for development—folate review
Abstract The Biomarkers of Nutrition for Development (BOND) project is designed to provide
evidence-based advice to anyone with an interest in the role of nutrition in health …
evidence-based advice to anyone with an interest in the role of nutrition in health …
TETonic shift: biological roles of TET proteins in DNA demethylation and transcription
In many organisms, the methylation of cytosine in DNA has a key role in silencing'parasitic'
DNA elements, regulating transcription and establishing cellular identity. The recent …
DNA elements, regulating transcription and establishing cellular identity. The recent …
[HTML][HTML] In situ fixation redefines quiescence and early activation of skeletal muscle stem cells
State of the art techniques have been developed to isolate and analyze cells from various
tissues, aiming to capture their in vivo state. However, the majority of cell isolation protocols …
tissues, aiming to capture their in vivo state. However, the majority of cell isolation protocols …
[HTML][HTML] Folate and DNA methylation: a review of molecular mechanisms and the evidence for folate's role
KS Crider, TP Yang, RJ Berry, LB Bailey - Advances in nutrition, 2012 - Elsevier
ABSTRACT DNA methylation is an epigenetic modification critical to normal genome
regulation and development. The vitamin folate is a key source of the one carbon group …
regulation and development. The vitamin folate is a key source of the one carbon group …
Molecular genetics of colorectal cancer
ER Fearon - Annual Review of Pathology: Mechanisms of …, 2011 - annualreviews.org
Over the past three decades, molecular genetic studies have revealed some critical
mutations underlying the pathogenesis of the sporadic and inherited forms of colorectal …
mutations underlying the pathogenesis of the sporadic and inherited forms of colorectal …
Epigenetics and gene expression
ER Gibney, CM Nolan - Heredity, 2010 - nature.com
Transcription, translation and subsequent protein modification represent the transfer of
genetic information from the archival copy of DNA to the short-lived messenger RNA, usually …
genetic information from the archival copy of DNA to the short-lived messenger RNA, usually …
Structure and function of mammalian DNA methyltransferases
DNA methylation plays an important role in epigenetic signalling, having an impact on gene
regulation, chromatin structure, development and disease. Here, we review the structures …
regulation, chromatin structure, development and disease. Here, we review the structures …
DNA Methylation of the Gonadal Aromatase (cyp19a) Promoter Is Involved in Temperature-Dependent Sex Ratio Shifts in the European Sea Bass
Sex ratio shifts in response to temperature are common in fish and reptiles. However, the
mechanism linking temperature during early development and sex ratios has remained …
mechanism linking temperature during early development and sex ratios has remained …