De-escalation or abbreviation of dual antiplatelet therapy in acute coronary syndromes and percutaneous coronary intervention: a Consensus Statement from an …

DA Gorog, JL Ferreiro, I Ahrens, J Ako… - Nature Reviews …, 2023 - nature.com
Conventional dual antiplatelet therapy (DAPT) for patients with acute coronary syndromes
undergoing percutaneous coronary intervention comprises aspirin with a potent P2Y …

[HTML][HTML] Single antiplatelet therapy directly after percutaneous coronary intervention in non-ST-segment elevation acute coronary syndrome patients: the OPTICA …

NMR van der Sangen, BEPM Claessen, IT Küçük… - …, 2023 - ncbi.nlm.nih.gov
Background Early P2Y 12 inhibitor monotherapy has emerged as a promising alternative to
12 months of dual antiplatelet therapy following percutaneous coronary intervention (PCI) …

Inflammatory bowel disease and acute coronary syndromes: from pathogenesis to the fine line between bleeding and ischemic risk

M Pepe, E Carulli, C Forleo, M Moscarelli… - Inflammatory Bowel …, 2021 - academic.oup.com
Inflammatory bowel disease (IBD) is a pathological condition that first involves the
gastrointestinal wall but can also trigger a systemic inflammatory state and thus …

Real-world bleeding in patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI) and prescribed different combinations of …

M Pufulete, J Harris, K Pouwels, BC Reeves… - Open …, 2022 - openheart.bmj.com
Objective To estimate the incidence and HRs for bleeding for different dual antiplatelet
therapies (DAPT) in a real-world population with acute coronary syndrome (ACS) …

Bleeding after hospital discharge following acute coronary syndrome: incidence, types, timing, and predictors

N Ismail, KP Jordan, UT Kadam… - Journal of the …, 2019 - Am Heart Assoc
Background The incidence and predictors of bleeding after acute coronary syndrome are
unclear within the real‐world setting. Our objective was to determine the incidence, types …

Incidence and predictors of serious bleeding during long-term follow-up after acute coronary syndrome in a population-based cohort study

A Graipe, A Ulvenstam, AL Irevall, L Söderström… - Scientific Reports, 2021 - nature.com
Progress in decreasing ischemic complications in acute coronary syndrome (ACS) has
come at the expense of increased bleeding risk. We estimated the long-term, post-discharge …

Cost-effectiveness of clopidogrel vs. ticagrelor in patients of 70 years or older with non-ST-elevation acute coronary syndrome

WWA van den Broek, JG van Paassen… - European Heart …, 2023 - academic.oup.com
Abstract Objective The POPular AGE trial showed that clopidogrel significantly reduced
bleeding risk compared with ticagrelor without any signs of an increase in thrombotic events …

[HTML][HTML] Less bleeding by omitting aspirin in non-ST-segment elevation acute coronary syndrome patients: Rationale and design of the LEGACY study

NMR van der Sangen, IT Küçük, S Sivanesan… - American Heart …, 2023 - Elsevier
Background Early aspirin withdrawal, also known as P2Y 12-inhibitor monotherapy,
following percutaneous coronary intervention (PCI) for non-ST-segment elevation acute …

Impact of recurrent ischaemic and bleeding events on quality of life in patients with acute coronary syndrome: Insights from the FORCE-ACS registry

NMR van der Sangen, J Azzahhafi, DRPPCP Yin… - Open …, 2023 - openheart.bmj.com
Objective Patients with acute coronary syndrome (ACS) remain at high risk for recurrent
ischaemic and bleeding events during follow-up. Our study aimed to quantify and compare …

Safety and efficacy of combined dual antiplatelet therapy and factor VIII prophylaxis in patients with haemophilia A after acute coronary syndrome

P Agosti, SM Siboni, A Ciavarella, S Arcudi… - …, 2024 - Wiley Online Library
Introduction The increased life expectancy of patients with haemophilia A (HA) has led to a
growing prevalence of cardiovascular risk factors and events. There is still scarce evidence …