Francisella tularensis is a facultative intracellular gram-negative pathogen and the
etiological agent of the zoonotic disease tularemia. Recent advances in the field of …

Studies of immune responses to Francisella have been conducted for well over 50 years.
Here, the basic parameters of innate and adaptive immune responses to Francisella are …

Francisella tularensis is an obligate, intracellular bacterium that causes acute, lethal disease
following inhalation. As an intracellular pathogen F. tularensis must invade cells, replicate …

Developing efficacious vaccines against enteric diseases is a global challenge that requires
a better understanding of cellular recruitment dynamics at the mucosal surfaces. The current …

In recent years, studies on the intracellular pathogen Francisella tularensis have greatly
intensified, generating a wealth of new information on the interaction of this organism with …

Iron acquisition from the host is an important step in the pathogenic process. While Yersinia
pestis has multiple iron transporters, the yersiniabactin (Ybt) siderophore-dependent system …

Francisella tularensis can cause fatal respiratory tularemia in humans and animals and is
increasingly being isolated in the United States and several European countries. The …

The earliest known route of vaccination was respiratory, by intranasal insufflation of
powdered scab material containing variola virus from smallpox patients, reportedly practiced …

Francisella tularensis, the highly virulent etiologic agent of tularemia, is a low-dose
intracellular pathogen that is able to escape from the phagosome and replicate in the …

The role of Abs in protection against respiratory infection with the intracellular bacterium
Francisella tularensis is not clear. To investigate the ability of Abs to clear bacteria from the …