I 2-mediated coupling of quinazolinone enamines with 2-aminopyridines: a new strategy to access spiroquinazolinones

J Fang, Z Pan, T Liu, Y Rao, H Jiang… - Organic & Biomolecular …, 2023 - pubs.rsc.org
Herein, we report a novel, rapid and efficient route to the spiroquinazolinone framework via
an umpolung strategy mediated by molecular iodine. A library of functionalized …

A Synthetic Protocol for the Construction of Chroman‐Spiroquinazolin (thi) one Framework via a Metal‐Free, Three‐Component, Domino, Double Annulations

L Wang, S Li, X Xiao, W Xu, P Zhang… - Advanced Synthesis & …, 2022 - Wiley Online Library
A three‐component domino approach for the synthesis of chroman‐spiroquinazolin (thi)
ones is described. It involves a condensation of 2‐aminoacetophenones and iso (thio) …

Employing Visible-Light Photoredox Catalysis in Multicomponent–Multicatalyst Reactions: One-Pot Synthesis of Spiroquinazolin-2-(thi) ones

Z Pan, X Yang, B Chen, S Shi, T Liu… - The Journal of …, 2022 - ACS Publications
The multicomponent–multicatalyst reaction ((MC) 2R) and visible-light catalysis have
emerged as green and powerful strategies for achieving ideal syntheses. Here, we report …

Inactivation of the superoxide dismutase by malondialdehyde in the nonalcoholic fatty liver disease: a combined molecular docking approach to clinical studies

A Arya, N Azarmehr, M Mansourian… - … of physiology and …, 2021 - Taylor & Francis
The objective of the present study was to investigate the plasma levels of oxidative stress
markers and the activity of antioxidant enzymes in NAFLD and healthy subjects …

The protective effect of natural phenolic compound on the functional and structural responses of inhibited catalase by a common azo food dye

S Khataee, G Dehghan, R Yekta, S Rashtbari… - Food and Chemical …, 2022 - Elsevier
In this research retrieval effects of natural yellow (NY) on the performance of carmoisine
(CAR) inhibited bovine liver catalase (BLC) was studied using multispectral and theoretical …

Evaluation of oxidant and intracellular anti-oxidant activity in rheumatoid arthritis patients: In vivo and in silico studies

Y Oğul, F Gür, M Cengiz, B Gür, RA Sarı… - International …, 2021 - Elsevier
Rheumatoid Arthritis (RA) is the most prevalent cause of the systematic inflammatory arthritis
that destroys the joints. While the pathogenesis of RA remains to be clarified, the imbalance …

Environmentally Benign Synthesis of Quinoline–Spiroquinazolinones by Iron-Catalyzed Dehydrogenative [4+ 2] Cycloaddition of Secondary/Tertiary Anilines and 4 …

Y Ding, J Kuang, X Xiao, L Wang… - The Journal of Organic …, 2021 - ACS Publications
We report an efficient iron-catalyzed cross-dehydrogenative coupling [4+ 2] annulation of
secondary/tertiary anilines with quinazolinones to generate quinoline–spiroquinzolinones …

Apoptosis induction activity and molecular docking studies of survivin siRNA carried by Fe3O4-PEG-LAC-chitosan-PEI nanoparticles in MCF-7 human breast cancer …

S Arami, M Mahdavi, MR Rashidi, R Yekta… - … of pharmaceutical and …, 2017 - Elsevier
Delivery of small interfering RNAs (siRNAs) into cells still remains a challenge in gene
delivery studies. Here, we investigated the ability of synthesized Fe 3 O 4-PEG-LAC …

Phyto-synthesized silver nanoparticles from Sargassum subrepandum: anticancer, antimicrobial, and molluscicidal activities

H El-Sayed, A Abdelsalam, MY Morad… - Frontiers in Plant …, 2024 - frontiersin.org
In the realm of nanotechnology, the use of algae to produce nanoparticles is an
environmentally friendly, sustainable, and economically viable strategy. In the present study …

Activation of the glutathione peroxidase by metformin in the bile-duct ligation-induced liver injury: in vivo combined with molecular docking studies

M Mansourian, H Sadeghi… - Current Pharmaceutical …, 2018 - ingentaconnect.com
Background: Inhibition of hepatic fibrosis is an attainable objective in managing the chronic
liver disease. The present study aimed to investigate possible defensive effects of metformin …