Recent studies have indicated that combining oncolytic viruses with CAR-T cells in therapy
has shown superior anti-tumor effects, representing a promising approach. Nonetheless, the …

Methods The relationship between IGF2BP3 and immune cell infiltration was analyzed using
online bioinformatics tools. Knockout of IGF2BP3 in mouse hepatoma cell line Hepa1-6 was …

合成生物学有望创造具备独特优势的抗肿瘤微生物疫苗, 合成生物学改造的微生物更能适应肿瘤
微环境并在其中富集与增殖, 削弱或者逆转免疫抑制细胞的功能, 并增强肿瘤抗原的呈递 …

Glioblastoma is the most common malignant primary brain tumor in adults. The prognosis is
extremely poor even with standard treatment of maximal safe resection, radiotherapy, and …

A cardiac glycoside epoxide,(−)-cryptanoside A (1), was isolated from the stems of
Cryptolepis dubia collected in Laos, for which the complete structure was confirmed by …

Glioma is a diverse category of tumors originating from glial cells encompasses various
subtypes, based on the specific type of glial cells involved. The most aggressive is …

Screening approved library is a promising and safe strategy to overcome the limitation of low
response rate and drug resistance in immunotherapy. Accumulating evidences showed that …

Glioblastoma (GBM), the predominant and primary malignant intracranial tumor, poses a
formidable challenge due to its immunosuppressive microenvironment, thereby confounding …

Oncolytic viruses (OVs) are emerging as therapeutically relevant anticancer agents as
contemporary immunotherapy gains traction. Furthermore, OVs are an ideal platform for …

Oncolytic viruses (OVs) represent an emerging immunotherapeutic strategy owing to their
capacity for direct tumor lysis and induction of antitumor immunity. However, hurdles like …