Resveratrol derivatives as potential treatments for Alzheimer's and Parkinson's disease

BD Arbo, C André-Miral, RG Nasre-Nasser… - Frontiers in aging …, 2020 - frontiersin.org
Neurodegenerative diseases are characterized by the progressive loss of neurons in
different regions of the nervous system. Alzheimer's disease (AD) and Parkinson's disease …

Neuroprotective effects of anthocyanins and its major component cyanidin-3-O-glucoside (C3G) in the central nervous system: An outlined review

J Zhang, J Wu, F Liu, L Tong, Z Chen, J Chen… - European journal of …, 2019 - Elsevier
Anthocyanins, a class of water soluble flavonoids extracted from plants like berries and
soybean seed, have been shown to display obvious anti-oxidative, anti-inflammatory, and …

[HTML][HTML] Berberine protects against 6-OHDA-induced neurotoxicity in PC12 cells and zebrafish through hormetic mechanisms involving PI3K/AKT/Bcl-2 and Nrf2/HO-1 …

C Zhang, C Li, S Chen, Z Li, X Jia, K Wang, J Bao… - Redox biology, 2017 - Elsevier
Berberine (BBR) is a renowned natural compound that exhibits potent neuroprotective
activities. However, the cellular and molecular mechanisms are still unclear. Hormesis is an …

An outline for the pharmacological effect of icariin in the nervous system

J Jin, H Wang, X Hua, D Chen, C Huang… - European Journal of …, 2019 - Elsevier
Icariin is a major active component of the traditional herb Epimedium, also known as Horny
Goat Weed. It has been extensively studied throughout the past several years and is known …

Recent trends in the development of nanophytobioactive compounds and delivery systems for their possible role in reducing oxidative stress in Parkinson's disease …

P Ganesan, HM Ko, IS Kim, DK Choi - International journal of …, 2015 - Taylor & Francis
Oxidative stress plays a very critical role in neurodegenerative diseases, such as
Parkinson's disease (PD), which is the second most common neurodegenerative disease …

Therapeutic potential of baicalein in Alzheimer's disease and Parkinson's disease

Y Li, J Zhao, C Hölscher - CNS drugs, 2017 - Springer
Alzheimer's disease and Parkinson's disease are the two most common, progressive central
neurodegenerative diseases affecting the population over the age of 60 years. Apart from …

Modulation of α-synuclein fibrillation by plant metabolites, daidzein, fisetin and scopoletin under physiological conditions

AR Rane, H Paithankar, RV Hosur… - International Journal of …, 2021 - Elsevier
The aggregation of α-synuclein is linked to neurological disorders, and of these, Parkinson's
disease (PD) is among the most widely studied. In this background, we have investigated …

GRP78/BIP/HSPA5 as a therapeutic target in models of Parkinson's disease: a mini review

AB Enogieru, SI Omoruyi, DC Hiss… - … in Pharmacological and …, 2019 - Wiley Online Library
Parkinson's disease (PD) is a common neurodegenerative disorder characterized by
selective loss of dopamine neurons in the substantia nigra pars compacta of the midbrain …

Botanical drug puerarin coordinates with nerve growth factor in the regulation of neuronal survival and neuritogenesis via activating ERK 1/2 and PI 3K/Akt signaling …

J Zhao, YY Cheng, W Fan, CB Yang… - CNS neuroscience & …, 2015 - Wiley Online Library
Aim Nerve growth factor (NGF) regulates neuronal survival and differentiation by activating
extracellular signal‐regulated‐kinases (ERK) 1/2 and phosphoinositide‐3‐kinase (PI …

Zebrafish: A promising in vivo model for assessing the delivery of natural products, fluorescence dyes and drugs across the blood-brain barrier

Y Li, T Chen, X Miao, X Yi, X Wang, H Zhao… - Pharmacological …, 2017 - Elsevier
The blood brain barrier (BBB) is the network of capillaries that controls the passage of
substances from the blood into the brain and other parts of the central nervous system …