Inflammation and atherosclerosis: signaling pathways and therapeutic intervention

P Kong, ZY Cui, XF Huang, DD Zhang… - Signal transduction and …, 2022 - nature.com
Atherosclerosis is a chronic inflammatory vascular disease driven by traditional and
nontraditional risk factors. Genome-wide association combined with clonal lineage tracing …

[HTML][HTML] Pyroptosis in inflammatory diseases and cancer

Z Rao, Y Zhu, P Yang, Z Chen, Y Xia, C Qiao, W Liu… - Theranostics, 2022 - ncbi.nlm.nih.gov
Pyroptosis is a lytic and inflammatory type of programmed cell death that is usually triggered
by inflammasomes and executed by gasdermin proteins. The main characteristics of …

Interleukins in cancer: from biology to therapy

D Briukhovetska, J Dörr, S Endres, P Libby… - Nature Reviews …, 2021 - nature.com
Interleukins and associated cytokines serve as the means of communication for innate and
adaptive immune cells as well as non-immune cells and tissues. Thus, interleukins have a …

Interleukin-18 cytokine in immunity, inflammation, and autoimmunity: Biological role in induction, regulation, and treatment

SA Ihim, SD Abubakar, Z Zian, T Sasaki… - Frontiers in …, 2022 - frontiersin.org
Interleukin-18 (IL-18) is a potent pro-inflammatory cytokine involved in host defense against
infections and regulates the innate and acquired immune response. IL-18 is produced by …

Role of the inflammasome in liver disease

M de Carvalho Ribeiro, G Szabo - Annual Review of Pathology …, 2022 - annualreviews.org
The involvement of inflammasomes in the proinflammatory response observed in chronic
liver diseases, such as alcohol-associated liver disease (ALD) and nonalcoholic fatty liver …

Selected biomarkers of depression: what are the effects of cytokines and inflammation?

S Harsanyi, I Kupcova, L Danisovic, M Klein - International journal of …, 2022 - mdpi.com
Depression is one of the leading mental illnesses worldwide and lowers the quality of life of
many. According to WHO, about 5% of the worldwide population suffers from depression …

A journey from structure to function of bacterial lipopolysaccharides

F Di Lorenzo, KA Duda, R Lanzetta, A Silipo… - Chemical …, 2021 - ACS Publications
Lipopolysaccharide (LPS) is a crucial constituent of the outer membrane of most Gram-
negative bacteria, playing a fundamental role in the protection of bacteria from …

Neuroinflammation in Alzheimer's disease

IG Onyango, GV Jauregui, M Čarná, JP Bennett Jr… - Biomedicines, 2021 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disease associated with human aging.
Ten percent of individuals over 65 years have AD and its prevalence continues to rise with …

Antioxidant, Anti-Inflammatory and Cytotoxic Activity of Phenolic Compound Family Extracted from Raspberries (Rubus idaeus): A General Review

AV Lopez-Corona, I Valencia-Espinosa… - Antioxidants, 2022 - mdpi.com
Raspberries (Rubus idaeus) possess a wide phenolic family profile; this serves the role of
self-protection for the plant. Interest in these compounds have significantly increased, since …

The role of the NLRP3 inflammasome and pyroptosis in cardiovascular diseases

S Toldo, A Abbate - Nature Reviews Cardiology, 2024 - nature.com
An intense, stereotyped inflammatory response occurs in response to ischaemic and non-
ischaemic injury to the myocardium. The NACHT, LRR and PYD domains-containing protein …