Ankylosing spondylitis (AS), a common type of spondyloarthropathy, is a chronic
inflammatory autoimmune disease that mainly affects spine joints, causing severe, chronic …

Ankylosing spondylitis (AS) is an inflammatory autoimmune disease. AS is a prototype form
of spondyloarthropathies (SpA). The precise etiology of AS has not been fully understood …

Inflammatory bowel diseases (IBDs) are a group of chronic inflammatory conditions mainly
of the colon and small intestine. Crohn's disease (CD) and ulcerative colitis (UC) are the …

Introduction The treatment of rheumatoid arthritis (RA) patients with anti-tumor necrosis
factor alpha (TNFα) biological drugs has dramatically improved the prognosis of these …

PURPOSE: To evaluate intravenously administered ultrasmall superparamagnetic iron
oxide (USPIO) as a marker of macrophage activity in an experimental rabbit model of …

Background: Uncontrolled studies suggest that granulocyteaphaeresis might be useful in the
management of active ulcerative colitis. Aim: To assess the efficacy of …

Apoptosis is a programmed physiological death of unwanted cells, and handling of apoptotic
cells (ACs) is thought to have profound effects on immune-mediated disorders. However …

Background. Recently, granulocyte and monocyte adsorption apheresis (GMA) has been
shown to be effective for active ulcerative colitis (UC). Its original weekly treatment schedule …

Pyoderma gangrenosum (PG), a chronic aseptic inflammatory skin disease characterized by
skin ulcers with elevated and undermined borders, is resistant to conventional therapies. PG …

Objective. To assess the efficacy and safety of adsorptive granulocyte and monocyte
apheresis (GCAP) in patients with refractory rheumatoid arthritis (RA). Methods. Patients …