Epigenetic responses and the developmental origins of health and disease
D Goyal, SW Limesand, R Goyal - Journal of Endocrinology, 2019 - joe.bioscientifica.com
Maternal and paternal factors influence offspring development and program its genome for
successful postnatal life. Based on the stressors during gestation, the pregnant female …
successful postnatal life. Based on the stressors during gestation, the pregnant female …
Establishing, maintaining and modifying DNA methylation patterns in plants and animals
JA Law, SE Jacobsen - Nature Reviews Genetics, 2010 - nature.com
Cytosine DNA methylation is a stable epigenetic mark that is crucial for diverse biological
processes, including gene and transposon silencing, imprinting and X chromosome …
processes, including gene and transposon silencing, imprinting and X chromosome …
Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells
K Blaschke, KT Ebata, MM Karimi, JA Zepeda-Martínez… - Nature, 2013 - nature.com
DNA methylation is a heritable epigenetic modification involved in gene silencing,
imprinting, and the suppression of retrotransposons. Global DNA demethylation occurs in …
imprinting, and the suppression of retrotransposons. Global DNA demethylation occurs in …
A unique regulatory phase of DNA methylation in the early mammalian embryo
DNA methylation is highly dynamic during mammalian embryogenesis. It is broadly
accepted that the paternal genome is actively depleted of 5-methylcytosine at fertilization …
accepted that the paternal genome is actively depleted of 5-methylcytosine at fertilization …
DNA methylation dynamics in health and disease
Y Bergman, H Cedar - Nature structural & molecular biology, 2013 - nature.com
DNA methylation is an epigenetic mark that is erased in the early embryo and then re-
established at the time of implantation. In this Review, dynamics of DNA methylation during …
established at the time of implantation. In this Review, dynamics of DNA methylation during …
Linking DNA methylation and histone modification: patterns and paradigms
H Cedar, Y Bergman - Nature Reviews Genetics, 2009 - nature.com
Both DNA methylation and histone modification are involved in establishing patterns of gene
repression during development. Certain forms of histone methylation cause local formation …
repression during development. Certain forms of histone methylation cause local formation …
DNA methylation patterns and epigenetic memory
A Bird - Genes & development, 2002 - genesdev.cshlp.org
The character of a cell is defined by its constituent proteins, which are the result of specific
patterns of gene expression. Crucial determinants of gene expression patterns are DNA …
patterns of gene expression. Crucial determinants of gene expression patterns are DNA …
[HTML][HTML] DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
M Okano, DW Bell, DA Haber, E Li - Cell, 1999 - cell.com
The establishment of DNA methylation patterns requires de novo methylation that occurs
predominantly during early development and gametogenesis in mice. Here we demonstrate …
predominantly during early development and gametogenesis in mice. Here we demonstrate …
Epigenetic reprogramming in mammalian development
DNA methylation is a major epigenetic modification of the genome that regulates crucial
aspects of its function. Genomic methylation patterns in somatic differentiated cells are …
aspects of its function. Genomic methylation patterns in somatic differentiated cells are …
Genomic imprinting: parental influence on the genome
Genomic imprinting affects several dozen mammalian genes and results in the expression of
those genes from only one of the two parental chromosomes. This is brought about by …
those genes from only one of the two parental chromosomes. This is brought about by …