Abstract Changes in synaptic efficacy are thought to be crucial to experience-dependent
modifications of neural function. The diversity of mechanisms underlying these changes is …

In the late 1990's, a series of experiments carried out independently in two laboratories led
to establish an important connection between the function of the endocannabinoids, which …

Several cannabinoid compounds present therapeutic properties, but also have psychotropic
effects, limiting their use as medicine. Nowadays, many important discoveries on the …

The endogenous cannabinoid (endocannabinoid) system regulates a diverse array of
physiological processes and unsurprisingly possesses considerable potential targets for the …

Since the discovery of endocannabinoids and their receptors, two major members of the
endocannabinoid family, anandamide (AEA) and 2-arachidonoylglycerol (2-AG), have been …

Δ9-Tetrahydrocannabinol (the active ingredient of marijuana), as well as endogenous and
synthetic cannabinoids, exert many biological functions by activating two types of …

The endogenous C18 N-acylethanolamines (NAEs) N-linolenoylethanolamine (18: 3 NAE),
N-linoleoylethanolamine (18: 2 NAE), N-oleoylethanolamine (18: 1 NAE), and N …

Abstract Pepcan-12 (RVD-hemopressin; RVDPVNFKLLSH) is the major peptide of a family
of endogenous peptide endocannabinoids (pepcans) shown to act as negative allosteric …

The endocannabinoid signaling system is composed of the cannabinoid receptors; their
endogenous ligands, the endocannabinoids; the enzymes that produce and inactivate the …

We investigated whether prostaglandin ethanolamides (prostamides) E2, F2α, and D2 exert
some of their effects by 1) activating prostanoid receptors either per se or after conversion …