Background A single-nucleotide polymorphism (Gly460Trp) within the α-adducin gene
(ADD1) may influence several renal phenotypes, including salt sensitivity, susceptibility to …

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Nonalcoholic fatty liver disease (NAFLD) and chronic kidney disease (CKD) share common
pathogenic mechanisms and risk factors. We aim to evaluate the association between …

Mounting evidence supports the central role of oxidative stress and inflammation in obesity
and the development of hypertension. However, most studies focusing on the non-enzymatic …

Because dopamine D 1 receptors (DRD1) influence renal sodium transport and vascular
hemodynamics, we examined whether genetic polymorphisms play a role in renal function …

Abstract Background Recently, the American Heart Association developed a set of 3 ideal
cardiovascular (CV) health factors. However, information on whether associations of uric …

Abstract Background and Aims In experimental investigations conducted in rats, raising
serum uric acid (SUA) levels resulted in the stimulation of intrarenal renin expression …

Gouty arthritis, often referred to simply as gout, is a disorder of purine metabolism
characterized by the deposition of monosodium urate monohydrate (MSU) crystals in …

Background: Elevated serum uric acid (UA) levels are associated with adverse outcomes in
ST-segment elevation myocardial infarction (STEMI) patients undergoing primary …

Aim: The Losartan Intervention For Endpoint reduction in hypertension (LIFE) study showed
less new-onset atrial fibrillation (AF) in hypertensive patients receiving losartan-vs. atenolol …