An overview of Nrf2 signaling pathway and its role in inflammation

S Saha, B Buttari, E Panieri, E Profumo, L Saso - Molecules, 2020 - mdpi.com
Inflammation is a key driver in many pathological conditions such as allergy, cancer,
Alzheimer's disease, and many others, and the current state of available drugs prompted …

Medicinal plants as sources of active molecules against COVID-19

B Benarba, A Pandiella - Frontiers in pharmacology, 2020 - frontiersin.org
The Severe Acute Respiratory Syndrome-related Coronavirus 2 (SARS-CoV-2) or novel
coronavirus (COVID-19) infection has been declared world pandemic causing a worrisome …

Early nutritional supplementation in non-critically ill patients hospitalized for the 2019 novel coronavirus disease (COVID-19): Rationale and feasibility of a shared …

R Caccialanza, A Laviano, F Lobascio, E Montagna… - Nutrition, 2020 - Elsevier
Abstract Objectives Beginning in December 2019, the 2019 novel coronavirus disease
(COVID-19) has caused a pneumonia epidemic that began in Wuhan, China, and is rapidly …

Host serine proteases: a potential targeted therapy for COVID-19 and influenza

Y Rahbar Saadat, SM Hosseiniyan Khatibi… - Frontiers in Molecular …, 2021 - frontiersin.org
The ongoing pandemic illustrates limited therapeutic options for controlling SARS-CoV-2
infections, calling a need for additional therapeutic targets. The viral spike S glycoprotein …

Micronutrients and bioactive substances: Their potential roles in combating COVID-19

TS Keflie, HK Biesalski - Nutrition, 2021 - Elsevier
Objectives The coronavirus disease 2019 (COVID-19) pandemic is seriously threatening
public health and setting off huge economic crises across the world. In the absence of …

Pathogenesis of COVID‐19 described through the lens of an undersulfated and degraded epithelial and endothelial glycocalyx

HN du Preez, C Aldous, MR Hayden… - The FASEB …, 2022 - Wiley Online Library
The glycocalyx surrounds every eukaryotic cell and is a complex mesh of proteins and
carbohydrates. It consists of proteoglycans with glycosaminoglycan side chains, which are …

Diseases with health disparities as drivers of COVID‐19 outcome

JT Moore, W Pilkington, D Kumar - Journal of Cellular and …, 2020 - Wiley Online Library
The COVID‐19 pandemic has forced our society to come face to face with complex issues
that were once theoretical but are now being played out in real time. As data from the …

N‐Acetylcysteine and Other Sulfur‐Donors as a Preventative and Adjunct Therapy for COVID‐19

HN du Preez, C Aldous, HG Kruger… - Advances in …, 2022 - Wiley Online Library
The airway epithelial glycocalyx plays an important role in preventing severe acute
respiratory syndrome coronavirus 2 entry into the epithelial cells, while the endothelial …

Developing inhaled protein therapeutics for lung diseases

AA Matthews, PLR Ee, R Ge - Molecular biomedicine, 2020 - Springer
Biologic therapeutics such as protein/polypeptide drugs are conventionally administered
systemically via intravenous injection for the treatment of diseases including lung diseases …

SARS-CoV-2 infection susceptibility influenced by ACE2 genetic polymorphisms: insights from Tehran Cardio-Metabolic Genetic Study

H Lanjanian, M Moazzam-Jazi, M Hedayati… - Scientific reports, 2021 - nature.com
The genetic variations among individuals are one of the notable factors determining disease
severity and drug response. Nowadays, COVID-19 pandemic has been adversely affecting …