The first closed bilayer phospholipid systems, called liposomes, were described in 1965 and
soon were proposed as drug delivery systems. The pioneering work of countless liposome …

Active targeting that exploits the (over) expression of surface receptors in target cells by
ligand incorporation is a central concept in nanomedicine research. Despite unprecedented …

Nanomedicines have significant potential for cancer treatment. Although the majority of
nanomedicines currently tested in clinical trials utilize simple, biocompatible liposome …

It has long been recognized that the physical form of materials can mediate their toxicity—
the health impacts of asbestiform materials, industrial aerosols, and ambient particulate …

With the objective to formulate multifunctional nanosized liposomes to target amyloid
deposits in Alzheimer Disease (AD) brains, a lipid–PEG–curcumin derivative was …

Observing and visualizing objects, with the help of tools, which cannot be seen with the
naked eye, had always raised curiosity among the scientific community and given scientific …

Monoclonal antibodies (mAbs) are an important class of therapeutic agents approved for the
therapy of many types of malignancies. However, in certain cases applications of …

Accumulation of amyloid peptide (Aβ) in senile plaques is a hallmark lesion of Alzheimer
disease (AD). The design of molecules able to target the amyloid pathology in tissue is …

Particle-based nanosensors have over the past decade been designed for optical
fluorescent-based ratiometric measurements of pH in living cells. However, quantitative and …

Liposomes have been exploited for pharmaceutical purposes, including diagnostic imaging
and drug and gene delivery. The versatility of liposomes as drug carriers has been …