[HTML][HTML] Intestinal mycobiota in health and diseases: from a disrupted equilibrium to clinical opportunities

X Wu, Y Xia, F He, C Zhu, W Ren - Microbiome, 2021 - Springer
Bacteria, viruses, protozoa, and fungi establish a complex ecosystem in the gut. Like other
microbiota, gut mycobiota plays an indispensable role in modulating intestinal physiology …

Plasma membrane MCC/eisosome domains promote stress resistance in fungi

CE Lanze, RM Gandra, JE Foderaro… - Microbiology and …, 2020 - Am Soc Microbiol
There is growing appreciation that the plasma membrane orchestrates a diverse array of
functions by segregating different activities into specialized domains that vary in size …

[HTML][HTML] The correlation between cell and nucleus size is explained by an eukaryotic cell growth model

Y Wu, AF Pegoraro, DA Weitz, P Janmey… - PLoS computational …, 2022 - journals.plos.org
In eukaryotes, the cell volume is observed to be strongly correlated with the nuclear volume.
The slope of this correlation depends on the cell type, growth condition, and the physical …

[HTML][HTML] Cell-cell metabolite exchange creates a pro-survival metabolic environment that extends lifespan

C Correia-Melo, S Kamrad, R Tengölics, CB Messner… - Cell, 2023 - cell.com
Metabolism is deeply intertwined with aging. Effects of metabolic interventions on aging
have been explained with intracellular metabolism, growth control, and signaling. Studying …

Food by-product valorisation in nutrients through spent brewer's yeast bioprocessing with Propionibacterium freudenreichii

M Kruk, P Varmanen, M Edelmann… - Journal of Cleaner …, 2024 - Elsevier
This study investigated the potential of Propionibacterium freudenreichii to enhance the
nutritional quality of spent brewer's yeast (SBY) by producing short-chain fatty acids (SCFAs) …

[HTML][HTML] Cell cycle-linked vacuolar pH dynamics regulate amino acid homeostasis and cell growth

V Okreglak, R Ling, M Ingaramo, NH Thayer… - Nature …, 2023 - nature.com
Amino acid homeostasis is critical for many cellular processes. It is well established that
amino acids are compartmentalized using pH gradients generated between organelles and …

Proteome reallocation from amino acid biosynthesis to ribosomes enables yeast to grow faster in rich media

J Björkeroth, K Campbell, C Malina… - Proceedings of the …, 2020 - National Acad Sciences
Several recent studies have shown that the concept of proteome constraint, ie, the need for
the cell to balance allocation of its proteome between different cellular processes, is …

Insights into the mechanisms of transport and regulation of the arabidopsis high-affinity K+ transporter HAK51

R Ródenas, P Ragel, M Nieves-Cordones… - Plant …, 2021 - academic.oup.com
The high-affinity K+ transporter HAK5 from Arabidopsis (Arabidopsis thaliana) is essential
for K+ acquisition and plant growth at low micromolar K+ concentrations. Despite its …

[HTML][HTML] Screening of Saccharomyces cerevisiae metabolite transporters by 13C isotope substrate labeling

LD Stanchev, I Møller-Hansen, P Lojko… - Frontiers in …, 2023 - frontiersin.org
The transportome of Saccharomyces cerevisiae comprises approximately 340 membrane-
bound proteins, of which very few are well-characterized. Elucidating transporter proteins' …

The metabolostasis network and the cellular depository of aggregation‐prone metabolites

SA Levkovich, E Gazit… - Angewandte Chemie …, 2023 - Wiley Online Library
The vital role of metabolites across all branches of life and their involvement in various
disorders have been investigated for decades. Many metabolites are poorly soluble in water …