[HTML][HTML] Mechanisms underlying the therapeutic effects of Qingfeiyin in treating acute lung injury based on GEO datasets, network pharmacology and molecular …
Y Wang, Y Yuan, W Wang, Y He, H Zhong… - Computers in biology …, 2022 - Elsevier
Background Qingfeiyin (QFY) is a common Chinese herbal formula for the treatment of acute
lung injury (ALI). However, its mechanisms of action are unclear. In this study, we …
lung injury (ALI). However, its mechanisms of action are unclear. In this study, we …
[HTML][HTML] Current strategies and technologies for finding drug targets of active components from traditional Chinese medicine
F Lu, D Wang, RL Li, LY He, L Ai… - Frontiers in Bioscience …, 2021 - imrpress.com
Introduction: The ambiguity of the drug target is one of the major factors restricting the
development of traditional Chinese medicine (TCMs) and its bioactive constituents. The …
development of traditional Chinese medicine (TCMs) and its bioactive constituents. The …
Shaoyao decoction attenuates DSS-induced ulcerative colitis, macrophage and NLRP3 inflammasome activation through the MKP1/NF-κB pathway
Y Wei, Y Fan, Y Ga, Y Zhang, J Han, Z Hao - Phytomedicine, 2021 - Elsevier
Background Shaoyao decoction (SYD), a traditional Chinese medicine prescription that
originated in the Jin-Yuan Dynasty, has shown effects in treating ulcerative colitis. However …
originated in the Jin-Yuan Dynasty, has shown effects in treating ulcerative colitis. However …
Defining the Role of Isoeugenol from Ocimum tenuiflorum against Diabetes Mellitus-Linked Alzheimer's Disease through Network Pharmacology and Computational …
The present study involves the integrated network pharmacology and phytoinformatics-
based investigation of phytocompounds from Ocimum tenuiflorum against diabetes mellitus …
based investigation of phytocompounds from Ocimum tenuiflorum against diabetes mellitus …
Application of network pharmacology in the study of mechanism of Chinese medicine in the treatment of ulcerative colitis: A review
S Zheng, T Xue, B Wang, H Guo, Q Liu - Frontiers in Bioinformatics, 2022 - frontiersin.org
Network pharmacology is a research method based on a multidisciplinary holistic analysis of
biological systems, which coincides with the idea of the holistic view of traditional Chinese …
biological systems, which coincides with the idea of the holistic view of traditional Chinese …
A practical strategy for exploring the pharmacological mechanism of luteolin against COVID-19/asthma comorbidity: findings of system pharmacology and …
YZ Xie, CW Peng, ZQ Su, HT Huang, XH Liu… - Frontiers in …, 2022 - frontiersin.org
Asthma patients may increase their susceptibility to SARS-CoV-2 infection and the poor
prognosis of coronavirus disease 2019 (COVID-19). However, anti-COVID-19/asthma …
prognosis of coronavirus disease 2019 (COVID-19). However, anti-COVID-19/asthma …
Mechanisms of Rhizoma Coptidis against type 2 diabetes mellitus explored by network pharmacology combined with molecular docking and experimental validation
W An, Y Huang, S Chen, T Teng, Y Shi, Z Sun, Y Xu - Scientific Reports, 2021 - nature.com
This study systematically explored the underlying mechanism of Rhizoma Coptidis against
type 2 diabetes mellitus (T2DM) by using network pharmacology and molecular docking and …
type 2 diabetes mellitus (T2DM) by using network pharmacology and molecular docking and …
Integrated network pharmacology and metabolomics reveal the mechanisms of Jasminum elongatum in anti-ulcerative colitis
J Qiu, G Xiao, M Yang, X Huang, D Cai, C Xie… - Scientific Reports, 2023 - nature.com
Jasminum elongatum (JE), an ethnic Chinese medicine, is widely used in the Lingnan
region of China, because of its analgesic and antidiarrheal action, as well as its anti …
region of China, because of its analgesic and antidiarrheal action, as well as its anti …
The pathogenic roles of IL-22 in colitis: its transcription regulation by musculin in T helper subsets and innate lymphoid cells
J Yan, J Yu, K Liu, Y Liu, C Mao, W Gao - Frontiers in immunology, 2021 - frontiersin.org
IL-22 plays a crucial role in promoting inflammation, antimicrobial immunity and tissue repair
at barrier surfaces. The role of IL-22 in colitis is still controversial: while IL-22 has a …
at barrier surfaces. The role of IL-22 in colitis is still controversial: while IL-22 has a …
Systems pharmacology study of the anti-liver injury mechanism of citri reticulatae pericarpium
J Wu, X Ye, S Yang, H Yu, L Zhong… - Frontiers in …, 2021 - frontiersin.org
Liver diseases are mostly triggered by oxidative stress and inflammation, leading to
extracellular matrix overproduction and prone to develop into liver fibrosis, cirrhosis and …
extracellular matrix overproduction and prone to develop into liver fibrosis, cirrhosis and …