Background Systemic lupus erythematosus (SLE) and primary Sjögren's syndrome (pSS)
are autoimmune disorders characterized by autoantibodies, dysregulated B cells, and …

Sex chromosomes are typically viewed as having originated from a pair of autosomes, and
differentiated as the sex-limited chromosome (eg Y) has degenerated by losing most genes …

The differences in morbidity and mortality patterns and life expectancy between the sexes
are well established in different infectious and parasitic conditions, such as in …

Sex‐specific transcriptional and epigenomic profiles are detectable in the embryo very soon
after fertilization. I propose that in male (XY) and female (XX) pre‐implantation embryos sex …

Several thousand sex-differential distal enhancers have been identified in mouse liver;
however, their links to sex-biased genes and the impact of any sex-differences in nuclear …

Background: We sought to test the hypothesis that transcriptome-level gene signatures are
differentially expressed between male and female bipolar patients, prior to lithium treatment …

Sex is an important variable in biology. Notable differences have been observed between
male and female Drosophila in regulation of metabolism, in response to nutritional …

In addition to sperm-related genes, the male-specific chromosome Y (chrY) contains a class
of ubiquitously expressed and evolutionary conserved dosage-sensitive regulator genes …

Hepatocellular carcinoma (HCC) is sexually disparate in humans, with a significantly
increased prevalence in males. The molecular mechanisms by which the inhibition or …

Leishmania infantum causes visceral leishmaniasis (VL) in Brazil. We previously observed
that VL is more common in males than females living in endemic neighborhoods, despite …