Alveolar dynamics and beyond–the importance of surfactant protein C and cholesterol in lung homeostasis and fibrosis
K Sehlmeyer, J Ruwisch, N Roldan… - Frontiers in …, 2020 - frontiersin.org
Surfactant protein C (SP-C) is an important player in enhancing the interfacial adsorption of
lung surfactant lipid films to the alveolar air-liquid interface. Doing so, surface tension drops …
lung surfactant lipid films to the alveolar air-liquid interface. Doing so, surface tension drops …
Heterozygous RTEL1 mutations are associated with familial pulmonary fibrosis
C Kannengiesser, R Borie, C Ménard… - European …, 2015 - Eur Respiratory Soc
Pulmonary fibrosis is a fatal disease with progressive loss of respiratory function. Defective
telomere maintenance leading to telomere shortening is a cause of pulmonary fibrosis, as …
telomere maintenance leading to telomere shortening is a cause of pulmonary fibrosis, as …
A novel surfactant protein C gene mutation associated with progressive respiratory failure in infancy
MKS Litao, D Hayes Jr, S Chiwane… - Pediatric …, 2017 - Wiley Online Library
Summary Mutations of the Surfactant Protein C (SPC) gene (SFTPC) have been associated
with childhood interstitial lung disease (chILD) with variable age of onset, severity of lung …
with childhood interstitial lung disease (chILD) with variable age of onset, severity of lung …
Cryptotanshinone is a candidate therapeutic agent for interstitial lung disease associated with a BRICHOS-domain mutation of SFTPC
M Hosokawa, R Mikawa, A Hagiwara, Y Okuno… - IScience, 2023 - cell.com
Interstitial lung disease (ILD) represents a large group of diseases characterized by chronic
inflammation and fibrosis of the lungs, for which therapeutic options are limited. Among …
inflammation and fibrosis of the lungs, for which therapeutic options are limited. Among …
Ethnic differences in idiopathic pulmonary fibrosis: The Japanese perspective
Epidemiologic data suggest that there are ethnic differences between Japanese and other
populations with regard to the important clinical aspects of interstitial lung disease (ILD) …
populations with regard to the important clinical aspects of interstitial lung disease (ILD) …
Surfactant protein C dysfunction with new clinical insights for diffuse alveolar hemorrhage and autoimmunity
X Tang, Y Shen, C Zhou, H Yang, H Liu, H Li… - Pediatric …, 2019 - mednexus.org
Importance: Surfactant protein C (SP-C) dysfunction is a rare disease associated with
interstitial lung disease. Early therapies may improve outcomes but the diagnosis is often …
interstitial lung disease. Early therapies may improve outcomes but the diagnosis is often …