A synopsis of the evidence for the science and clinical management of cardiovascular-kidney-metabolic (CKM) syndrome: a scientific statement from the American …

CE Ndumele, IJ Neeland, KR Tuttle, SL Chow… - Circulation, 2023 - Am Heart Assoc
A growing appreciation of the pathophysiological interrelatedness of metabolic risk factors
such as obesity and diabetes, chronic kidney disease, and cardiovascular disease has led …

RANKL/RANK/OPG pathway: A mechanism involved in exercise‐induced bone remodeling

M Tobeiha, MH Moghadasian, N Amin… - BioMed research …, 2020 - Wiley Online Library
Bones as an alive organ consist of about 70% mineral and 30% organic component. About
200 million people are suffering from osteopenia and osteoporosis around the world. There …

[HTML][HTML] Evolving concepts on inflammatory biomarkers and malnutrition in chronic kidney disease

F Graterol Torres, M Molina, J Soler-Majoral… - Nutrients, 2022 - mdpi.com
While patient care, kidney replacement therapy, and transplantation techniques for chronic
kidney disease (CKD) have continued to progress, the incidence of malnutrition disorders in …

Renal and extrarenal effects of fibroblast growth factor 23

M Vervloet - Nature Reviews Nephrology, 2019 - nature.com
Abstract Fibroblast growth factor 23 (FGF23) is a hormone with a central role in the
regulation of phosphate homeostasis. This regulation is accomplished by the coordinated …

Accelerated kidney aging in diabetes mellitus

J Guo, HJ Zheng, W Zhang, W Lou… - Oxidative Medicine …, 2020 - Wiley Online Library
With aging, the kidney undergoes inexorable and progressive changes in structural and
functional performance. These aging‐related alterations are more obvious and serious in …

The basics of phosphate metabolism

CA Wagner - Nephrology Dialysis Transplantation, 2024 - academic.oup.com
Phosphorus is an essential mineral that is, in the form of inorganic phosphate (Pi), required
for building cell membranes, DNA and RNA molecules, energy metabolism, signal …

Kidney dysfunction and the risk of developing aortic stenosis

G Vavilis, M Bäck, G Occhino, M Trevisan… - Journal of the American …, 2019 - jacc.org
Background Chronic kidney disease (CKD) and aortic stenosis (AS) share many risk factors.
Objectives This study sought to evaluate whether kidney dysfunction is associated with the …

[HTML][HTML] Early vascular ageing and cellular senescence in chronic kidney disease

L Dai, AR Qureshi, A Witasp, B Lindholm… - Computational and …, 2019 - Elsevier
Chronic kidney disease (CKD) is a clinical model of premature ageing characterized by
progressive vascular disease, systemic inflammation, muscle wasting and frailty. The …

[HTML][HTML] Hypertension is associated with osteoporosis: a case-control study in Chinese postmenopausal women

H Chai, J Ge, L Li, J Li, Y Ye - BMC Musculoskeletal Disorders, 2021 - Springer
Background Osteoporosis and cardiovascular disease (CVD) are age-related diseases. It is
reported that patients with CVD have a higher risk of bone loss. This retrospective study …

[HTML][HTML] Recommendations of the Spanish Society of Nephrology for the management of mineral and bone metabolism disorders in patients with chronic kidney …

JV Torregrosa, J Bover, MR Portillo, EG Parra… - Nefrología (English …, 2023 - Elsevier
As in 2011, when the Spanish Society of Nephrology (SEN) published the Spanish
adaptation to the Kidney Disease: Improving Global Outcomes (KDIGO) universal Guideline …