Vitamin A is an essential nutrient required throughout life. Through its various metabolites,
vitamin A sustains fetal development, immunity, vision, and the maintenance, regulation, and …

Cell cycle and apoptosis regulator 2 (CCAR2), also known as deleted in breast cancer 1
(DBC1), has been recently identified as a master regulator of transcriptional processes and …

Nuclear receptors (NRs) constitute a superfamily of ligand-activated transcription factors with
a paramount role in ubiquitous physiological functions such as metabolism, growth, and …

Arrival of multi-colored fluorescent proteins and advances in live cell imaging has
immensely contributed to our understanding of intracellular trafficking of nuclear receptors …

Nuclear receptors (NRs) form a family of druggable transcription factors that are regulated by
ligand binding to orchestrate multifaceted physiological functions, including reproduction …

The two estrogen receptors ERα and ERβ are nuclear receptors that bind estrogen (E2) and
function as ligand-inducible transcription factors. They are homologues and can form dimers …

The steroid hormone 20-hydroxy-ecdysone (20E) promotes proliferation in Drosophila wing
precursors at low titer but triggers proliferation arrest at high doses. Remarkably, wing …

Oral cancer has been a global concern for decades, with an estimated 377,713 new cases
and 177,757 deaths worldwide, according to the GLOBOCAN 2020. Despite extensive …

The genome of Caenorhabditis elegans encodes 284 nuclear hormone receptor, which
perform diverse functions in development and physiology. One of the best characterized of …

Endocrine-disrupting chemicals (EDCs) pose significant environmental and health risks due
to their potential to interfere with nuclear receptors (NRs), key regulators of physiological …