Psoriasis is a common inflammatory skin disease that is thought to be mediated by activated
T cells. In this study, the complementarity-determining region 3 (CDR3) in T cell receptors …

C57Bl/6 mice infected with mouse hepatitis virus, strain JHM (MHV-JHM) develop a chronic
demyelinating encephalomyelitis. Infectious virus can be isolated only from symptomatic …

Monitoring cytotoxic T lymphocyte (CTL) responses to tumor antigens that have been
defined at the molecular level has become essential to assess novel approaches to the …

Superanttgens reduce:. t% orous immune response by stimulating T cells that express
parucular T-cell receptor VI~ chains. Mouse mammary tumo; virus ts a nulk-transnutted …

A dominant gene carried in certain inbred mouse strains confers susceptibility to tumors
induced by polyoma virus. This gene, designated Pyvs, was defined in crosses between the …

During acute human viral infections, such as influenza A, specific cytotoxic T lymphocytes
(CTL) are generated which aid virus clearance. We have observed that in HLA-A* 0201+ …

The molecular interactions between the T‐cell receptor (TCR) and peptide‐MHC (pMHC)
have been elucidated in recent years. Nevertheless, the fact that binding of only slightly …

Anaplastic astrocytoma and glioblastoma are frequent and malignant brain tumors that are
infiltrated by T lymphocytes. Whether these cells result from non-specific inflammation …

Allergic responses are characterized by a biphasic response profile consisting of an
immediate reaction to an allergens followed by a late-phase response. Early allergic …

We examined T cell development and T cell repertoire in transgenic mice expressing a
single T cell receptor (TCR) α chain derived from the H‐2Db‐lymphocytic choriomeningitis …