SOTIP is a versatile method for microenvironment modeling with spatial omics data
The rapidly developing spatial omics generated datasets with diverse scales and modalities.
However, most existing methods focus on modeling dynamics of single cells while ignore …
However, most existing methods focus on modeling dynamics of single cells while ignore …
Rethinking the initial changes in subarachnoid haemorrhage: focusing on real-time metabolism during early brain injury
Over the last two decades, neurological researchers have uncovered many
pathophysiological mechanisms associated with subarachnoid haemorrhage (SAH), with …
pathophysiological mechanisms associated with subarachnoid haemorrhage (SAH), with …
Advancements in ToF-SIMS imaging for life sciences
In the last 2 decades, Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) has
gained significant prominence as a powerful imaging technique in the field of life sciences …
gained significant prominence as a powerful imaging technique in the field of life sciences …
Advances and challenges in spatial transcriptomics for developmental biology
K Choe, U Pak, Y Pang, W Hao, X Yang - Biomolecules, 2023 - mdpi.com
Development from single cells to multicellular tissues and organs involves more than just the
exact replication of cells, which is known as differentiation. The primary focus of research …
exact replication of cells, which is known as differentiation. The primary focus of research …
Microlensed fiber allows subcellular imaging by laser-based mass spectrometry
Mass spectrometry imaging (MSI) enables the chemical mapping of molecules and elements
in a label-free, high-throughput manner. Because this approach can be accomplished …
in a label-free, high-throughput manner. Because this approach can be accomplished …
Metabolic regulation of the hallmarks of stem cell biology
BT Jackson, LWS Finley - Cell stem cell, 2024 - cell.com
Stem cells perform many different functions, each of which requires specific metabolic
adaptations. Over the past decades, studies of pluripotent and tissue stem cells have …
adaptations. Over the past decades, studies of pluripotent and tissue stem cells have …
Metabolic control of innate lymphoid cells in health and disease
L Zhou, Q Lin, GF Sonnenberg - Nature metabolism, 2022 - nature.com
Innate lymphoid cells (ILCs) are a family of predominantly tissue-resident lymphocytes that
critically orchestrate immunity, inflammation, tolerance and repair at barrier surfaces of the …
critically orchestrate immunity, inflammation, tolerance and repair at barrier surfaces of the …
The interaction between ageing and Alzheimer's disease: insights from the hallmarks of ageing
Ageing is a crucial risk factor for Alzheimer's disease (AD) and is characterised by systemic
changes in both intracellular and extracellular microenvironments that affect the entire body …
changes in both intracellular and extracellular microenvironments that affect the entire body …
Harnessing computational spatial omics to explore the spatial biology intricacies
Z Yuan, J Yao - Seminars in Cancer Biology, 2023 - Elsevier
Spatially resolved transcriptomics (SRT) has unlocked new dimensions in our
understanding of intricate tissue architectures. However, this rapidly expanding field …
understanding of intricate tissue architectures. However, this rapidly expanding field …
Mapping breast cancer microenvironment through single-cell omics
Z Tan, C Kan, M Sun, F Yang, M Wong… - Frontiers in …, 2022 - frontiersin.org
Breast cancer development and progression rely not only on the proliferation of neoplastic
cells but also on the significant heterogeneity in the surrounding tumor microenvironment. Its …
cells but also on the significant heterogeneity in the surrounding tumor microenvironment. Its …