How the shape of embryos and organs emerges during development is a fundamental
question that has fascinated scientists for centuries. Tissue dynamics arise from a small set …

The way in which cells coordinate their behaviours during various biological processes,
including morphogenesis, cancer progression and tissue remodelling, largely depends on …

Intestinal organoids capture essential features of the intestinal epithelium such as crypt
folding, cellular compartmentalization and collective movements. Each of these processes …

During epithelial morphogenesis, E-cadherin adhesive junctions play an important part in
mechanically coupling the contractile cortices of cells together, thereby distributing the …

A long-term aim of the life sciences is to understand how organismal shape is encoded by
the genome. An important challenge is to identify mechanistic links between the genes that …

Tissue morphogenesis arises from coordinated changes in cell shape driven by actomyosin
contractions. Patterns of gene expression regionalize cell behaviours by controlling …

Collective cell contractions that generate global tissue deformations are a signature feature
of animal movement and morphogenesis. However, the origin of collective contractility in …

During organismal development, cells undergo complex changes in shape whose causal
relationship to individual morphogenetic processes remains unclear. The modular nature of …

One of the main research areas in biology from the mid‐1980s through the 1990s was the
elucidation of signaling pathways governing cell responses. These studies brought, among …

To survive, plants constantly adapt their body shape to their environment. This often involves
remarkably rapid bending of their organs such as stems, leaves and roots. Since plant cells …