Do interactions between gut ecology and environmental chemicals contribute to obesity and diabetes?

SM Snedeker, AG Hay - Environmental health perspectives, 2012 - ehp.niehs.nih.gov
Background: Gut microbiota are important factors in obesity and diabetes, yet little is known
about their role in the toxicodynamics of environmental chemicals, including those recently …

[PDF][PDF] Peroxisome proliferator-activated receptor-gamma: from adipogenesis to carcinogenesis

L Fajas, MB Debril, J Auwerx - Journal of molecular …, 2001 - researchgate.net
Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors, initially
described as molecular targets for synthetic compounds inducing peroxisome proliferation …

[HTML][HTML] Exposure to organophosphorus and organochlorine pesticides, perfluoroalkyl substances, and polychlorinated biphenyls in pregnancy and the association …

GD Shapiro, L Dodds, TE Arbuckle… - Environmental …, 2016 - Elsevier
Background Studies report increases in rates of gestational diabetes mellitus (GDM) over
recent decades. Environmental chemicals may increase the risk of diabetes through impacts …

Increased risk of diabetes and polychlorinated biphenyls and dioxins: a 24-year follow-up study of the Yucheng cohort

SL Wang, PC Tsai, CY Yang, Y Leon Guo - Diabetes care, 2008 - Am Diabetes Assoc
OBJECTIVE—Polychlorinated biphenyls (PCBs) and polychlorinated dibenzofurans
(PCDFs) are important and persistent organic pollutants (POPs) in humans. Recent cross …

Bisphenol‐A disruption of the endocrine pancreas and blood glucose homeostasis

AB Ropero, P Alonso‐Magdalena… - … journal of andrology, 2008 - Wiley Online Library
The link between endocrine disruptors and altered blood glucose homeostasis has been
recently suggested. Epidemiological studies have correlated levels of phthalates, dioxins …

Pesticide use and incident diabetes among wives of farmers in the Agricultural Health Study

AP Starling, DM Umbach, F Kamel, S Long… - Occupational and …, 2014 - oem.bmj.com
Objective To estimate associations between use of specific agricultural pesticides and
incident diabetes in women. Methods We used data from the Agricultural Health Study, a …

[HTML][HTML] Chronic consumption of farmed salmon containing persistent organic pollutants causes insulin resistance and obesity in mice

MM Ibrahim, E Fjære, EJ Lock, D Naville, H Amlund… - PloS one, 2011 - journals.plos.org
Background Dietary interventions are critical in the prevention of metabolic diseases. Yet,
the effects of fatty fish consumption on type 2 diabetes remain unclear. The aim of this study …

Persistent organic pollutants and β-cell toxicity: a comprehensive review

MP Hoyeck, G Matteo… - American Journal …, 2022 - journals.physiology.org
Persistent organic pollutants (POPs) are a diverse family of contaminants that show
widespread global dispersion and bioaccumulation. Humans are continuously exposed to …

Polychlorinated biphenyl (PCB) exposure and diabetes: results from the Anniston Community Health Survey

AE Silverstone, PF Rosenbaum… - Environmental …, 2012 - ehp.niehs.nih.gov
Background: Polychlorinated biphenyls (PCBs) manufactured in Anniston, Alabama, from
1929 to 1971 caused significant environmental contamination. The Anniston population …

Diabetes in relation to serum levels of polychlorinated biphenyls and chlorinated pesticides in adult Native Americans

N Codru, MJ Schymura, S Negoita, R Rej… - Environmental …, 2007 - ehp.niehs.nih.gov
Background Recent research suggests that diabetes, a condition whose incidence is
increasing, is associated with exposure to polychlorinated biphenyls (PCBs) and chlorinated …