Abstract Toll-like receptors (TLRs), which serve as a bridge between innate and adaptive
immunity, may be viable treatment targets. TLRs are the first line of defense against …

Imiquimod is a synthetic imidazoquinolone amine, which has potent immune response
modifier activity, when topically used. This characteristic property of imiquimod has led to its …

OBJECTIVE: To evaluate the histologic response rate of high-grade squamous
intraepithelial lesions (HSIL) of the cervix after topical application of 5% imiquimod cream …

Background Anogenital warts (AGW) can cause economic burden on healthcare systems
and are associated with emotional, psychological and physical issues. Objective To provide …

Actinic keratosis (AK) is a chronic skin disease in which multiple clinical and subclinical
lesions co-exist across large areas of sun-exposed skin, resulting in field cancerisation …

Surgical excision has been the preferred treatment for cutaneous malignancies, but can be
affected by various considerations. Noninvasive, self-administered topical treatments …

Primary cutaneous lymphomas comprise a group of lymphatic malignancies that occur
primarily in the skin. They represent the second most common form of extranodal non …

Background: Imiquimod 5% cream (Aldara®), a novel topical immune response modifier,
has been approved for the topical treatment of anogenital HPV-induced warts. In addition …

Human papillomavirus (HPV) encompasses a group of viruses that infect the skin and
mucous membranes. In the presence of certain factors, persistent infection with high‐risk …

Background Porokeratosis (PK) is a rare skin disease of unknown etiology. It consists of a
keratinization disorder, which may appear in several clinical forms and can undergo …