The lymphatic vasculature provides an essential route to drain fluid, macromolecules, and
immune cells from the interstitium as lymph, returning it to the bloodstream where the …

The lymphatic system is an integral part of the circulatory system and plays an important role
in the fluid homeostasis of the human body. Accumulating evidence has recently suggested …

BACKGROUND: Rheumatic heart disease is the major cause of valvular heart disease in
developing nations. Endothelial cells (ECs) are considered crucial contributors to rheumatic …

Cardiovascular diseases remain the largest cause of death worldwide with recent evidence
increasingly attributing the development and progression of these diseases to an …

Chronic kidney disease (CKD) involves progressive and irreversible loss of renal function,
often causing complications and comorbidities and impairing the function of various organs …

Rheumatic heart disease (RHD) is a major cause of valvular heart disease in developing
nations. Endothelial cells (ECs) are considered crucial contributors to RHD, but greater …

Lipid metabolism plays a critical role in lymphatic endothelial cell (LEC) development and
maintenance. Altered lipid metabolism is associated with loss of lymphatic vessel integrity …