PEER simplified lipid guideline 2023 update: Prevention and management of cardiovascular disease in primary care

MR Kolber, S Klarenbach, M Cauchon, M Cotterill… - Canadian Family …, 2023 - cfp.ca
Objective To update the 2015 clinical practice guideline and provide a simplified approach
to lipid management in the prevention of cardiovascular disease (CVD) for primary care …

Integrative polygenic risk score improves the prediction accuracy of complex traits and diseases

B Truong, LE Hull, Y Ruan, QQ Huang, W Hornsby… - Cell Genomics, 2024 - cell.com
Polygenic risk scores (PRSs) are an emerging tool to predict the clinical phenotypes and
outcomes of individuals. We propose PRSmix, a framework that leverages the PRS corpus …

Validation and comparison of cardiovascular risk prediction equations in Chinese patients with Type 2 diabetes

J Liang, Q Li, Z Fu, X Liu, P Shen, Y Sun… - European Journal of …, 2023 - academic.oup.com
Aims For patients with diabetes, the European guidelines updated the cardiovascular
disease (CVD) risk prediction recommendations using diabetes-specific models with age …

Validation of the European SCORE2 models in a Canadian primary care cohort

M Sud, A Sivaswamy, PC Austin… - European Journal of …, 2024 - academic.oup.com
Abstract Aims Systematic Coronary Risk Evaluation Model 2 (SCORE2) was recently
developed to predict atherosclerotic cardiovascular disease (ASCVD) in Europe. Whether …

Lupus nephropathy beyond immunosuppression: Searching for nephro and cardioprotection

E Morales, J Sandino, M Galindo - Frontiers in nephrology, 2023 - frontiersin.org
Renal involvement in systemic lupus erythematosus (SLE) represents one of the most
frequent organ manifestations, often leading to end-stage kidney disease (ESKD). Several …

Can we measurably improve the prediction of recurrent coronary artery disease events?

WS Weintraub, WE Boden - European Heart Journal, 2023 - search.ebscohost.com
In particular, the Framingham study established the importance of elevated LDL-cholesterol
and elevated blood pressure in prediction of cardiovascular events.[7] The strong …

Development and Validation of the CANHEART Population-Based Laboratory Prediction Models for Atherosclerotic Cardiovascular Disease

M Sud, A Sivaswamy, PC Austin… - Annals of Internal …, 2023 - acpjournals.org
Background: Prediction of atherosclerotic cardiovascular disease (ASCVD) in primary
prevention assessments exclusively with laboratory results may facilitate automated risk …

[PDF][PDF] Lignes directrices simplifiées de PEER sur les lipides: actualisation 2023: Prévention et prise en charge des maladies cardiovasculaires en soins primaires

MR Kolber, S Klarenbach, M Cauchon, M Cotterill… - Canadian Family …, 2023 - cfp.ca
Résumé Objectif Actualiser le guide de pratique clinique de 2015 et présenter une approche
simplifiée de la prise en charge des lipides dans la prévention des maladies …

Implications of Five Different Risk Models In Primary Prevention Guidelines

M Sud, A Sivaswamy, PC Austin… - … Journal-Quality of …, 2024 - academic.oup.com
Background A lack of consensus exists across guidelines as to which risk model should be
used for the primary prevention of cardiovascular disease (CVD). Our objective was to …

2-Step-Scores with optional nephropathology for the prediction of adverse outcomes for brain-dead donor kidneys in Eurotransplant

A Ernst, H Regele, C Chatzikyrkou… - Nephrology Dialysis …, 2024 - academic.oup.com
Background and hypothesis The decision for acceptance or discard of the increasingly rare
and marginal brain-dead donor kidneys in Eurotransplant (ET) countries has to be made …