Context-specific regulation of extracellular vesicle biogenesis and cargo selection
AC Dixson, TR Dawson, D Di Vizio… - … Reviews Molecular Cell …, 2023 - nature.com
To coordinate, adapt and respond to biological signals, cells convey specific messages to
other cells. An important aspect of cell–cell communication involves secretion of molecules …
other cells. An important aspect of cell–cell communication involves secretion of molecules …
[HTML][HTML] Regulation of phospholipid distribution in the lipid bilayer by flippases and scramblases
T Sakuragi, S Nagata - Nature Reviews Molecular Cell Biology, 2023 - nature.com
Cellular membranes function as permeability barriers that separate cells from the external
environment or partition cells into distinct compartments. These membranes are lipid …
environment or partition cells into distinct compartments. These membranes are lipid …
[HTML][HTML] Drugs that inhibit TMEM16 proteins block SARS-CoV-2 spike-induced syncytia
COVID-19 is a disease with unique characteristics that include lung thrombosis, frequent
diarrhoea, abnormal activation of the inflammatory response and rapid deterioration of lung …
diarrhoea, abnormal activation of the inflammatory response and rapid deterioration of lung …
Apoptosis, pyroptosis, and necroptosis—Oh my! The many ways a cell can die
N Ketelut-Carneiro, KA Fitzgerald - Journal of molecular biology, 2022 - Elsevier
Cell death is an essential process in all living organisms and occurs through different
mechanisms. The three main types of programmed cell death are apoptosis, pyroptosis, and …
mechanisms. The three main types of programmed cell death are apoptosis, pyroptosis, and …
The clearance of dead cells by efferocytosis
E Boada-Romero, J Martinez, BL Heckmann… - … reviews Molecular cell …, 2020 - nature.com
Multiple modes of cell death have been identified, each with a unique function and each
induced in a setting-dependent manner. As billions of cells die during mammalian …
induced in a setting-dependent manner. As billions of cells die during mammalian …
Interplay between platelets and coagulation
Haemostasis stops bleeding at the site of vascular injury and maintains the integrity of blood
vessels through clot formation. This regulated physiological process consists of complex …
vessels through clot formation. This regulated physiological process consists of complex …
Understanding the diversity of membrane lipid composition
T Harayama, H Riezman - Nature reviews Molecular cell biology, 2018 - nature.com
Cellular membranes are formed from a chemically diverse set of lipids present in various
amounts and proportions. A high lipid diversity is universal in eukaryotes and is seen from …
amounts and proportions. A high lipid diversity is universal in eukaryotes and is seen from …
Neuronal cell death
M Fricker, AM Tolkovsky, V Borutaite… - Physiological …, 2018 - journals.physiology.org
Neuronal cell death occurs extensively during development and pathology, where it is
especially important because of the limited capacity of adult neurons to proliferate or be …
especially important because of the limited capacity of adult neurons to proliferate or be …
Local externalization of phosphatidylserine mediates developmental synaptic pruning by microglia
N Scott‐Hewitt, F Perrucci, R Morini, M Erreni… - The EMBO …, 2020 - embopress.org
Neuronal circuit assembly requires the fine balance between synapse formation and
elimination. Microglia, through the elimination of supernumerary synapses, have an …
elimination. Microglia, through the elimination of supernumerary synapses, have an …
How macrophages deal with death
G Lemke - Nature Reviews Immunology, 2019 - nature.com
Tissue macrophages rapidly recognize and engulf apoptotic cells. These events require the
display of so-called eat-me signals on the apoptotic cell surface, the most fundamental of …
display of so-called eat-me signals on the apoptotic cell surface, the most fundamental of …