Overview of Proteus mirabilis pathogenicity and virulence. Insights into the role of metals

M Chakkour, Z Hammoud, S Farhat, A El Roz… - Frontiers in …, 2024 - frontiersin.org
Proteus mirabilis is a Gram-negative bacterium with exclusive molecular and biological
features. It is a versatile pathogen acclaimed for its distinct urease production, swarming …

[HTML][HTML] Relocating Glyceryl Trinitrate as an Anti-Virulence Agent against Pseudomonas aeruginosa and Serratia marcescens: Insights from Molecular and In Vivo …

SI Nazeih, MAM Ali, ASA Halim, H Al-Lawati, HA Abbas… - Microorganisms, 2023 - mdpi.com
The problem of antibiotic resistance is a global critical public health concern. In light of the
threat of returning to the pre-antibiotic era, new alternative approaches are required such as …

Investigating Sulforaphane's anti-virulence and anti-quorum sensing properties against Pseudomonas aeruginosa

MM Bendary, MAM Ali, AS Abdel Halim… - Frontiers in …, 2024 - frontiersin.org
Background P. aeruginosa, a significant bacterium, can cause severe illness and resistance
to antibiotics. Quorum sensing (QS) systems regulate virulence factors production. Targeting …

[HTML][HTML] Thymoquinone is a natural antibiofilm and pathogenicity attenuating agent in Pseudomonas aeruginosa

MW Al-Rabia, HZ Asfour, NA Alhakamy… - Frontiers in Cellular …, 2024 - frontiersin.org
Pseudomonas aeruginosa belongs to the critical pathogens that represent a global public
health problem due to their high rate of resistance as listed by WHO. P. aeruginosa can …

[HTML][HTML] Redirecting pantoprazole as a metallo-beta-lactamase inhibitor in carbapenem-resistant Klebsiella pneumoniae

WH Abdulaal, NA Alhakamy, AH Asseri… - Frontiers in …, 2024 - frontiersin.org
The development of resistance to carbapenems in Klebsiella pneumoniae due to the
production of metallo-β-lactamases (MBLs) is a critical public health problem because …

[HTML][HTML] The anti-staphylococcal fusidic acid as an efflux pump inhibitor combined with fluconazole against vaginal candidiasis in mouse model

SE Gomaa, HA Abbas, FA Mohamed, MAM Ali… - BMC microbiology, 2024 - Springer
Background Candida albicans is the most common fungus that causes vaginal candidiasis
in immunocompetent women and catastrophic infections in immunocompromised patients …

Bacteriophage‐cocktail hydrogel dressing to prevent multiple bacterial infections and heal diabetic ulcers in mice

SJ Shiue, MS Wu, YH Chiang… - Journal of Biomedical …, 2024 - Wiley Online Library
Bacteriophage (phage) has been reported to reduce the bacterial infection in delayed‐
healing wounds and, as a result, aiding in the healing of said wounds. In this study we …

Surveillance of Enterobacteriaceae from Diabetic Foot Infections in a Tunisian Hospital: Detection of E. coli-ST131-bla CTX-M-15 and K. pneumoniae-ST1-blaNDM-1 …

A Arfaoui, S Martínez-Álvarez, IN Abdullahi… - Microbial Drug …, 2024 - liebertpub.com
The study determined the prevalence, antimicrobial resistant (AMR) determinants, and
genetic characteristics of Escherichia coli and Klebsiella pneumoniae isolates from patients …

[HTML][HTML] The Anti-Virulence Activities of the Antihypertensive Drug Propranolol in Light of Its Anti-Quorum Sensing Effects against Pseudomonas aeruginosa and …

HF Alotaibi, H Alotaibi, KM Darwish, ES Khafagy… - Biomedicines, 2023 - mdpi.com
The development of bacterial resistance is an increasing global concern that requires
discovering new antibacterial agents and strategies. Bacterial quorum sensing (QS) systems …

The Metabolic Characteristics of Patients at the Risk for Diabetic Foot Ulcer: A Comparative Study of Diabetic Patients with and without Diabetic Foot

X Li, S Wen, M Dong, Y Yuan, M Gong… - Diabetes, Metabolic …, 2023 - Taylor & Francis
Backgrounds and Objective Diabetic foot is a relatively severe complication in patients with
type 2 diabetes (T2D), with peripheral neuropathy and angiopathy frequently serving as risk …