Metallic scaffold with micron-scale geometrical cues promotes osteogenesis and angiogenesis via the ROCK/Myosin/YAP pathway

Y Liu, Q Yang, Y Wang, M Lin, Y Tong… - ACS Biomaterials …, 2022 - ACS Publications
The advent of precision manufacturing has enabled the creation of pores in metallic
scaffolds with feature size in the range of single microns. In orthopedic implants, pore …

[HTML][HTML] Research progress and clinical translation of three-dimensional printed porous tantalum in orthopaedics

J Ying, H Yu, L Cheng, J Li, B Wu, L Song… - Biomaterials …, 2023 - ncbi.nlm.nih.gov
With continuous developments in additive manufacturing technology, tantalum (Ta) metal
has been manufactured into orthopaedic implants with a variety of forms, properties and …

Partially melted Ti6Al4V particles increase bacterial adhesion and inhibit osteogenic activity on 3D-printed implants: an in vitro study

K Xie, Y Guo, S Zhao, L Wang, J Wu, J Tan… - Clinical Orthopaedics …, 2019 - journals.lww.com
Background A porous Ti6Al4V implant that is manufactured using selective laser melting
(SLM) has broad potential applications in the field of orthopaedic implants. The pore …

Current trends and future scope in 3D printing for surgical management of spine pathologies

N Kumar, SA Ramakrishnan, KG Lopez, BZ Chin… - Bioprinting, 2022 - Elsevier
Abstract 3D printing technology has increasing applications in spine surgery due to its many
realised and potential benefits. This review aims to explore the current and future potential of …

[HTML][HTML] Mediation of mechanically adapted TiCu/TiCuN/CFR-PEEK implants in vascular regeneration to promote bone repair in vitro and in vivo

Y Guo, C Chen, S Zhang, L Ren, Y Zhao… - Journal of Orthopaedic …, 2022 - Elsevier
Abstract Background/Objective TiCu/TiCuN is a multilayer composite coating comprising TiN
and Cu, which provides excellent wear resistance and antibacterial properties. However, its …

[HTML][HTML] Material-based therapy for bone nonunion

Y Leng, F Yang, Q Wang, Z Li, B Yuan, C Peng, G Ren… - Materials & Design, 2019 - Elsevier
Bone nonunion has become one of the most severe sequelae of fractures, infections, bone
tumors, or revision arthroplasty owing to its high morbidity and disability rate. Recently, bone …

Functionalized TiCu/TiCuN coating promotes osteoporotic fracture healing by upregulating the Wnt/β-catenin pathway

J Tan, L Ren, K Xie, L Wang, W Jiang… - Regenerative …, 2023 - academic.oup.com
Osteoporosis results in decreased bone mass and insufficient osteogenic function. Existing
titanium alloy implants have insufficient osteoinductivity and delayed/incomplete fracture …

[HTML][HTML] 3D printed osteochondral scaffolds: design strategies, present applications and future perspectives

G Liu, X Wei, Y Zhai, J Zhang, J Li, Z Zhao… - … in Bioengineering and …, 2024 - frontiersin.org
Articular osteochondral (OC) defects are a global clinical problem characterized by loss of
full-thickness articular cartilage with underlying calcified cartilage through to the …

Application of additively manufactured bone scaffold: a systematic review

Q Shi, J Chen, J Chen, Y Liu, H Wang - Biofabrication, 2024 - iopscience.iop.org
The application of additive manufacturing (AM) technology plays a significant role in various
fields, incorporating a wide range of cutting-edge technologies such as aerospace, medical …

[HTML][HTML] Advancements in Additive Manufacturing of Tantalum via the Laser Powder Bed Fusion (PBF-LB/M): A Comprehensive Review

AUH Mohsan, D Wei - Materials, 2023 - mdpi.com
Additive manufacturing (AM) exhibits a prime increment in manufacturing technology
development. The last few decades have witnessed massive improvement in this field of …