Interferon-γ and infectious diseases: Lessons and prospects
Infectious diseases continue to claim many lives. Prevention of morbidity and mortality from
these diseases would benefit not just from new medicines and vaccines but also from a …
these diseases would benefit not just from new medicines and vaccines but also from a …
[HTML][HTML] Effect of anti-COVID-19 drugs on patients with cancer
W Huang, W Liu, T Yu, Z Zhang, L Zhai… - European Journal of …, 2024 - Elsevier
The clinical treatment of patients with cancer who are also diagnosed with coronavirus
disease (COVID-19) has been a challenging issue since the outbreak of COVID-19 …
disease (COVID-19) has been a challenging issue since the outbreak of COVID-19 …
Interferon-γ as a Potential Inhibitor of SARS-CoV-2 ORF6 Accessory Protein
E Krachmarova, P Petkov, E Lilkova… - International Journal of …, 2024 - mdpi.com
The ORF6 protein of the SARS-CoV-2 virus plays a crucial role in blocking the innate
immune response of the infected cells by inhibiting interferon pathways. Additionally, it binds …
immune response of the infected cells by inhibiting interferon pathways. Additionally, it binds …
The Impact of Cytokines on Coagulation Profile in COVID-19 Patients: Controlled for Socio-Demographic, Clinical, and Laboratory Parameters
M Milentijević, N Katanić, B Joksimović, A Pavlović… - Biomedicines, 2024 - mdpi.com
Background: Severe coagulation abnormalities are common in patients with COVID-19
infection. We aimed to investigate the relationship between pro-inflammatory cytokines and …
infection. We aimed to investigate the relationship between pro-inflammatory cytokines and …
[HTML][HTML] The inflammatory microenvironment of the lung at the time of infection governs innate control of SARS-CoV-2 replication
PJ Baker, AC Bohrer, E Castro, EP Amaral… - bioRxiv, 2024 - ncbi.nlm.nih.gov
SARS-CoV-2 infection leads to vastly divergent clinical outcomes ranging from
asymptomatic infection to fatal disease. Co-morbidities, sex, age, host genetics and vaccine …
asymptomatic infection to fatal disease. Co-morbidities, sex, age, host genetics and vaccine …