[HTML][HTML] The regulation of bone metabolism and disorders by Wnt signaling
K Maeda, Y Kobayashi, M Koide, S Uehara… - International journal of …, 2019 - mdpi.com
Wnt, a secreted glycoprotein, has an approximate molecular weight of 40 kDa, and it is a
cytokine involved in various biological phenomena including ontogeny, morphogenesis …
cytokine involved in various biological phenomena including ontogeny, morphogenesis …
WNT signaling in cardiac and vascular disease
S Foulquier, EP Daskalopoulos, G Lluri… - Pharmacological …, 2018 - ASPET
WNT signaling is an elaborate and complex collection of signal transduction pathways
mediated by multiple signaling molecules. WNT signaling is critically important for …
mediated by multiple signaling molecules. WNT signaling is critically important for …
The role of the wnt/β-catenin signaling pathway in formation and maintenance of bone and teeth
P Duan, LF Bonewald - The international journal of biochemistry & cell …, 2016 - Elsevier
The Wnt signaling pathway is known as one of the important molecular cascades that
regulate cell fate throughout lifespan. The Wnt signaling pathway is further separated into …
regulate cell fate throughout lifespan. The Wnt signaling pathway is further separated into …
[HTML][HTML] Epigenetic plasticity drives adipogenic and osteogenic differentiation of marrow-derived mesenchymal stem cells
Terminal differentiation of multipotent stem cells is achieved through a coordinated cascade
of activated transcription factors and epigenetic modifications that drive gene transcription …
of activated transcription factors and epigenetic modifications that drive gene transcription …
[HTML][HTML] Progress of wnt signaling pathway in osteoporosis
Y Gao, N Chen, Z Fu, Q Zhang - Biomolecules, 2023 - mdpi.com
Osteoporosis, one of the serious health diseases, involves bone mass loss, bone density
diminishing, and degeneration of bone microstructure, which is accompanied by a tendency …
diminishing, and degeneration of bone microstructure, which is accompanied by a tendency …
Novel mechanisms of exosome-mediated phagocytosis of dead cells in injured heart
Rationale: After myocardial ischemic injury, improper phagocytic clearance of dying cardiac
cells and the ensuing lack of inflammation resolution results in adverse cardiac remodeling …
cells and the ensuing lack of inflammation resolution results in adverse cardiac remodeling …
[HTML][HTML] Deciphering the relevance of bone ECM signaling
Bone mineral density, a bone matrix parameter frequently used to predict fracture risk, is not
the only one to affect bone fragility. Other factors, including the extracellular matrix (ECM) …
the only one to affect bone fragility. Other factors, including the extracellular matrix (ECM) …
The role of the microenvironment in controlling the fate of bioprinted stem cells
The field of tissue engineering and regenerative medicine has made numerous advances in
recent years in the arena of fabricating multifunctional, three-dimensional (3D) tissue …
recent years in the arena of fabricating multifunctional, three-dimensional (3D) tissue …
Extracellular matrix stiffness and Wnt/β-catenin signaling in physiology and disease
P Astudillo - Biochemical Society Transactions, 2020 - portlandpress.com
The Wnt/β-catenin signaling pathway plays fundamental roles during development, stem cell
differentiation, and homeostasis, and its abnormal activation can lead to diseases. In recent …
differentiation, and homeostasis, and its abnormal activation can lead to diseases. In recent …
Down-regulated lncRNA MEG3 promotes osteogenic differentiation of human dental follicle stem cells by epigenetically regulating Wnt pathway
L Deng, H Hong, X Zhang, D Chen, Z Chen… - Biochemical and …, 2018 - Elsevier
Our previous long noncoding RNA (lncRNA) microarray results showed that lncRNA MEG3
(maternally expressed 3) was significantly downregulated in human dental follicle cells than …
(maternally expressed 3) was significantly downregulated in human dental follicle cells than …