Heavy drinking and alcohol use disorder are major public health problems. Practitioners not
specialising in alcohol treatment are often unaware of the guidelines for preventing …

Addictive disorders are partly heritable, chronic, relapsing conditions that account for a
tremendous disease burden. Currently available addiction pharmacotherapies are only …

In 2013, the American Heart Association and American College of Cardiology published the
“Guideline on Lifestyle Management to Reduce Cardiovascular Risk,” which was based on a …

Backgrounds. The prevalence of diabetes has increased with the increase of obesity, and
finding indicators to predict diabetes risk has become an urgent need. The purpose of this …

Heterogeneity of alcohol use disorder: understanding mechanisms to advance personalized
treatment. - Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe PMC …

BACKGROUND: There is a large treatment gap in alcohol dependence, and current
treatments are only moderately effective in preventing relapse. New treatment modalities …

This study evaluated the efficacy of as-needed use of the opioid system modulator
nalmefene in reducing alcohol consumption in patients with alcohol dependence. Seven …

Objectives: To assess the efficacy and safety of varenicline (Chantix) for the treatment of
alcohol dependence. Varenicline is a partial α4β2 nicotinic acetylcholine agonist approved …

Alcohol use disorders affect millions of individuals worldwide. Alcohol consumption is
directly associated with liver disease mortality and accounts for elevated social and …

Alcohol consumption is a complex trait determined by both genetic and environmental
factors, and is correlated with the risk of alcohol use disorders. Although a small number of …