Valorization of citrus peel waste for the sustainable production of value-added products

P Sharma, R Vishvakarma, K Gautam, A Vimal… - Bioresource …, 2022 - Elsevier
Globally the generation and mismanagement of waste from fruit processing and post-harvest
impose a severe burden on waste management strategies along with environmental …

Interplay of energy metabolism and autophagy

Y Feng, Y Chen, X Wu, J Chen, Q Zhou, B Liu… - Autophagy, 2024 - Taylor & Francis
Macroautophagy/autophagy, is widely recognized for its crucial role in enabling cell survival
and maintaining cellular energy homeostasis during starvation or energy stress. Its …

Complete biosynthesis of noscapine and halogenated alkaloids in yeast

Y Li, S Li, K Thodey, I Trenchard… - Proceedings of the …, 2018 - National Acad Sciences
Microbial biosynthesis of plant natural products from simple building blocks is a promising
approach toward scalable production and modification of high-value compounds. The …

Glucose starvation induces a switch in the histone acetylome for activation of gluconeogenic and fat metabolism genes

WC Hsieh, BM Sutter, H Ruess, SD Barnes, VS Malladi… - Molecular cell, 2022 - cell.com
Acetyl-CoA is a key intermediate situated at the intersection of many metabolic pathways.
The reliance of histone acetylation on acetyl-CoA enables the coordination of gene …

Carbon catabolite repression in filamentous fungi

M Adnan, W Zheng, W Islam, M Arif… - International Journal of …, 2017 - mdpi.com
Carbon Catabolite Repression (CCR) has fascinated scientists and researchers around the
globe for the past few decades. This important mechanism allows preferential utilization of …

Pathways shaping the mitochondrial inner membrane

T Klecker, B Westermann - Open Biology, 2021 - royalsocietypublishing.org
Mitochondria are complex organelles with two membranes. Their architecture is determined
by characteristic folds of the inner membrane, termed cristae. Recent studies in yeast and …

Glycerol metabolism and transport in yeast and fungi: established knowledge and ambiguities

M Klein, S Swinnen, JM Thevelein… - Environmental …, 2017 - Wiley Online Library
There is huge variability among yeasts with regard to their efficiency in utilizing glycerol as
the sole source of carbon and energy. Certain species show growth rates with glycerol …

Metabolic engineering of yeast for the production of carbohydrate-derived foods and chemicals from C1–3 molecules

H Tang, L Wu, S Guo, W Cao, W Ma, X Wang, J Shen… - Nature Catalysis, 2024 - nature.com
The increase in population-related and environmental issues has emphasized the need for
more efficient and sustainable production strategies for foods and chemicals. Carbohydrates …

Engineering a microbial biosynthesis platform for de novo production of tropane alkaloids

P Srinivasan, CD Smolke - Nature communications, 2019 - nature.com
Tropane alkaloids (TAs) are a class of phytochemicals produced by plants of the nightshade
family used for treating diverse neurological disorders. Here, we demonstrate de novo …

[HTML][HTML] Refactoring the upper sugar metabolism of Pseudomonas putida for co-utilization of cellobiose, xylose, and glucose

P Dvořák, V de Lorenzo - Metabolic engineering, 2018 - Elsevier
Given its capacity to tolerate stress, NAD (P) H/NAD (P) balance, and increased ATP levels,
the platform strain Pseudomonas putida EM42, a genome-edited derivative of the soil …