Severe sepsis is almost invariably associated with systemic activation of coagulation. There
is ample evidence that demonstrates a wide-ranging cross-talk between hemostasis and …

Disseminated intravascular coagulation (DIC) is an acquired syndrome characterized by
widespread intravascular activation of coagulation that can be caused by infectious insults …

Sepsis is one of the leading causes of deaths world-wide and yet there are no therapies
available other than ICU treatment. The patient outcome is determined by a complex …

Since the onset of the global pandemic in early 2020, coronavirus disease 2019 (COVID-19)
has posed a multitude of challenges to health care systems worldwide. In order to combat …

The acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure in
critically ill patients and is defined by the acute onset of noncardiogenic pulmonary oedema …

The coagulopathy of acute sepsis : Current Opinion in Anesthesiology The coagulopathy of
acute sepsis : Current Opinion in Anesthesiology Log in or Register Subscribe to journalSubscribe …

Abstract Lipoprotein (a)(Lp (a)) is associated with atherothrombosis through several
mechanisms, including putative antifibrinolytic properties. However, genetic association …

The human newborn infant is susceptible to gut inflammatory disorders. In particular, growth-
restricted infants or infants born prematurely may develop a severe form of intestinal …

Severe sepsis, defined as sepsis with acute organ dysfunction, is associated with high
morbidity and mortality rates. The development of novel therapies for sepsis is critically …

cofactors V and VIII by thrombin, and (3) thrombin-induced factor XI activation, leading to
additional factors IXa and Xa. The assembly of several complexes, such as the “tenase …