Glycoconjugate vaccine using a genetically modified O antigen induces protective antibodies to Francisella tularensis
G Stefanetti, N Okan, A Fink… - Proceedings of the …, 2019 - National Acad Sciences
Francisella tularensis is the causative agent of tularemia, a category A bioterrorism agent.
The lipopolysaccharide (LPS) O antigen (OAg) of F. tularensis has been considered for use …
The lipopolysaccharide (LPS) O antigen (OAg) of F. tularensis has been considered for use …
[HTML][HTML] Working correlates of protection predict SchuS4-derived-vaccine candidates with improved efficacy against an intracellular bacterium, Francisella tularensis
R De Pascalis, B Frey, HM Rice, V Bhargava, TH Wu… - npj Vaccines, 2022 - nature.com
Francisella tularensis, the causative agent of tularemia, is classified as Tier 1 Select Agent
with bioterrorism potential. The efficacy of the only available vaccine, LVS, is uncertain and it …
with bioterrorism potential. The efficacy of the only available vaccine, LVS, is uncertain and it …
[HTML][HTML] An improved tobacco mosaic virus (TMV)-conjugated multiantigen subunit vaccine against respiratory tularemia
AA Mansour, S Banik, RV Suresh, H Kaur… - Frontiers in …, 2018 - frontiersin.org
Francisella tularensis, the causative agent of the fatal human disease known as tularemia is
classified as a Category A Select Agent by the Centers for Disease Control. No licensed …
classified as a Category A Select Agent by the Centers for Disease Control. No licensed …
Francisella tularensis
Francisella tularensis is a facultative intracellular pathogen that causes the zoonotic disease
tularemia. Transmission can occur through arthropod vectors, by inhalation, ingestion, and …
tularemia. Transmission can occur through arthropod vectors, by inhalation, ingestion, and …
Interplay of carbohydrate and carrier in antibacterial glycoconjugate vaccines
Bacterial infections are a serious health concern and are responsible for millions of illnesses
and deaths each year in communities around the world. Vaccination is an important public …
and deaths each year in communities around the world. Vaccination is an important public …
Expanding Francisella models: pairing up the soil amoeba Dictyostelium with aquatic Francisella
Y Brenz, HC Winther-Larsen, M Hagedorn - International Journal of …, 2018 - Elsevier
The bacterial genus Francisella comprises highly pathogenic species that infect mammals,
arthropods, fish and protists. Understanding virulence and host defense mechanisms of …
arthropods, fish and protists. Understanding virulence and host defense mechanisms of …
Tularemia: clinical manifestations, diagnosis, treatment, and prevention
RL Penn, MS Edwards - 2019 - uptodate.com
Tularemia is a zoonotic infection caused by Francisella tularensis, an aerobic and fastidious
gram-negative bacterium. Human infection occurs following contact with infected animals or …
gram-negative bacterium. Human infection occurs following contact with infected animals or …
[HTML][HTML] Intranasal administration of a two-dose adjuvanted multi-antigen TMV-subunit conjugate vaccine fully protects mice against Francisella tularensis LVS …
AA McCormick, A Shakeel, C Yi, H Kaur, AM Mansour… - PLoS …, 2018 - journals.plos.org
Tularemia is a fatal human disease caused by Francisella tularensis, a Gram-negative
encapsulated coccobacillus bacterium. Due to its low infectious dose, ease of aerosolized …
encapsulated coccobacillus bacterium. Due to its low infectious dose, ease of aerosolized …
Characterization of Inner and Outer Membrane Proteins from Francisella tularensis Strains LVS and Schu S4 and Identification of Potential Subunit Vaccine …
Francisella tularensis is the causative agent of tularemia and a potential bioterrorism agent.
In the present study, we isolated, identified, and quantified the proteins present in the …
In the present study, we isolated, identified, and quantified the proteins present in the …
[HTML][HTML] Structural and biophysical properties of FopA, a major outer membrane protein of Francisella tularensis
Francisella tularensis is an extremely infectious pathogen and a category A bioterrorism
agent. It causes the highly contagious zoonosis, Tularemia. Currently, FDA approved …
agent. It causes the highly contagious zoonosis, Tularemia. Currently, FDA approved …