Macrophages are crucial innate immune cells that maintain tissue homeostasis and defend
against pathogens; however, their infiltration into tumors has been associated with adverse …

Breast cancer remains a significant clinical concern affecting millions of women worldwide.
Immunotherapy is a rapidly growing drug class that has revolutionized cancer treatment but …

Tenosynovial giant cell tumor (TGCT) is a neoplasm of the joint synovium that can have
severe impacts on joint mobility, function, and quality of life. Traditionally, treatment …

Macrophages represent an important component of the innate immune system. Under
physiological conditions, macrophages, which are essential phagocytes, maintain a …

Cold tumors lack antitumor immunity and are resistant to therapy, representing a major
challenge in cancer medicine. Because of the immunosuppressive spirit of the tumor …

Drawing from the findings presented in this thesis, the cover portrays the abstract dissection
of the immune microenvironment of breast cancer. The colors derived from the tumor …

Living cells can be engineered into cell-based therapeutics by utilizing synthetic genetic
elements and protein effectors that reprogram cell activity to be able to treat diseases …

Breast cancer is the most diagnosed form of cancer in New Zealand, with the majority of
breast cancer associated deaths attributed to metastasis. During the metastatic cascade …

It has been widely known that macrophages play critical roles during infection and immune
responses. While as tumor-infiltrating myeloid cells, macrophages accumulated in the tumor …

SnoRNAs have robust potential functions and therapeutic value in breast cancer. Herein, we
investigated the role SNORA5A in breast cancer. This study reviewed samples from TCGA …