There is a great current interest in developing target-specific radiopharmaceuticals for early
detection of diseases and radiotherapy of cancers. This critical review will focus on the role …

Cyclams are 14-membered tetraamine macrocycles which bind strongly to a wide range of
metal ions. Medical interest has centred on clinical trials of a bicyclam for the treatment of …

The synthesis of a new ligand (1) containing a single phenanthroline (phen) chromophore
and a flexibly connected diethylenetriamine tetracarboxylic acid unit (DTTA) as a lanthanide …

Macrocyclic chelators and their metal complexes have widespread applications in the
biomedical sciences, including radiopharmaceutical chemistry. The use of copper …

A series of 1, 4, 8, 11-tetraazabicyclo [6.6. 2] hexadecane ligands, including the parent
compound, N, N '-dialkyl variants, and the first N, N '-di-pendant-arm derivatives have been …

A comparison of complexing properties of cyclen and cyclam derivatives containing acetic
acid pendant arms on one hand and their methylphosphonic or methylphosphinic acid …

Efficient bifunctional gallium-68 chelators for positron emission tomography: tris(hydroxypyridinone)
ligands - Chemical Communications (RSC Publishing) DOI:10.1039/C1CC12123E Royal …

Given the practical advantages of the 68Ga isotope in positron emission tomography
applications, gallium complexes are gaining increasing importance in biomedical imaging …

Advances in the biomedical sciences have been accelerated by the introduction of many
new imaging technologies in recent years. With animal models widely used in the basic and …

For application in positron emission tomography (PET), PrP9, a N, N′, N′′‐trisubstituted
triazacyclononane with methyl (2‐carboxyethyl) phosphinic acid pendant arms, was …