Bis (thiosemicarbazones) as bifunctional chelators for the room temperature 64-copper labeling of peptides

R Hueting, M Christlieb, JR Dilworth, EG Garayoa… - Dalton …, 2010 - pubs.rsc.org
A range of new carboxylate functionalised bis (thiosemicarbazone) ligands and their Cu (II)
complexes have been prepared, fully characterised and radiolabeled in high yield with both …

Lower Ligand Denticity Leading to Improved Thermodynamic and Kinetic Stability of the Gd3+ Complex: The Strange Case of OBETA

Z Baranyai, M Botta, M Fekete… - … A European Journal, 2012 - Wiley Online Library
Polyaminocarboxylic ligands are widely employed in several applications involving the
formation of stable metal ion complexes.[1] Extremely high stability is required for complexes …

Bis (methylphosphonic acid) derivatives of 1, 4, 8, 11-tetraazacyclotetradecane (cyclam). Synthesis, crystal and molecular structures, and solution properties

J Kotek, P Vojtíšek, I Císařová… - Collection of …, 2000 - cccc.uochb.cas.cz
Cyclam derivatives with methylphosphonic acid arms in position 1, 8 and substituent R= H,
Me, CH 2 Ph in positions 4 and 11 are synthesised by Mannich reaction of an appropriate …

DNA cleavage and antimicrobial investigation of Co (II), Ni (II), and Cu (II) complexes with triazole Schiff bases: synthesis and spectral characterization

AD Kulkarni, SA Patil, VH Naik, PS Badami - Medicinal chemistry research, 2011 - Springer
Abstract The Co (II), Ni (II), and Cu (II) complexes with Schiff bases derived from 3-
substituted-4-amino-5-mercapto-1, 2, 4-triazole and fluvastatin have been synthesized …

Bifunctional 3-hydroxy-4-pyridinone derivatives as potential pharmaceuticals: synthesis, complexation with Fe(III), Al(III) and Ga(III) and in vivo evaluation with 67Ga

MA Santos, M Gil, L Gano, S Chaves - JBIC Journal of Biological Inorganic …, 2005 - Springer
A series of extra-functionalized 3-hydroxy-4-pyridinone chelators of hard metal ions,
containing different side-chains with peptidomimetic groups, was studied to assess the effect …

A Chiral Molecular Conductor: Synthesis, Structure, and Physical Properties of [ET] 3 [Sb2 (l-tart) 2]⊙ CH3CN (ET= Bis (ethylendithio) tetrathiafulvalene; l-tart=(2 R, 3 …

E Coronado, JR Galán-Mascarós… - Inorganic …, 2004 - ACS Publications
The salt [ET] 3 [Sb2 (l-tart) 2]⊙ CH3CN (1) has been obtained by electrocrystallization of the
organic donor bis (ethylendithio) tetrathiafulvalene (ET or BEDT-TTF) in the presence of the …

Copper, nickel, and zinc cyclam–amino acid and cyclam–peptide complexes may be synthesized with “click” chemistry and are noncytotoxic

M Yu, JR Price, P Jensen, CJ Lovitt, T Shelper… - Inorganic …, 2011 - ACS Publications
We describe the synthesis of cyclam metal complexes derivatized with amino acids or a
tripeptide using a copper (I)-catalyzed Huisgen “click” reaction. The linker triazole formed …

Magnetic resonance contrast agents for medical and molecular imaging

MJ Allen, TJ Meade - Metal ions in biological systems, 2004 - api.taylorfrancis.com
This chapter focuses on the wide range of chemical and biological applications that exist for
magnetic resonance imaging (MRI) contrast agents. We begin with a brief introduction of …

Conformational analysis and synthetic approaches to polydentate perhydro-diazepine ligands for the complexation of gallium (III)

D Parker, BP Waldron - Organic & Biomolecular Chemistry, 2013 - pubs.rsc.org
Synthetic approaches are reported to polydentate ligands based on 6-phenyl-6-amino-
perhydro-1, 4-diazepine. The synthetic route devised averts ring-opening reactions, allowing …

Contrast agents for magnetic resonance imaging synthesized with ring-opening metathesis polymerization

MJ Allen, RT Raines, LL Kiessling - Journal of the American …, 2006 - ACS Publications
A monomer for ring-opening metathesis polymerization (ROMP) has been developed that
also functions as a portion of a GdIII chelating moiety for a magnetic resonance imaging …