Nutrient-sensing mechanisms and pathways

A Efeyan, WC Comb, DM Sabatini - Nature, 2015 - nature.com
The ability to sense and respond to fluctuations in environmental nutrient levels is a requisite
for life. Nutrient scarcity is a selective pressure that has shaped the evolution of most cellular …

Fatty acid transport and signaling: mechanisms and physiological implications

D Samovski, M Jacome-Sosa… - Annual review of …, 2023 - annualreviews.org
Long-chain fatty acids (FAs) are components of plasma membranes and an efficient fuel
source and also serve as metabolic regulators through FA signaling mediated by membrane …

Scavenger receptors in homeostasis and immunity

J Canton, D Neculai, S Grinstein - Nature Reviews Immunology, 2013 - nature.com
Scavenger receptors were originally identified by their ability to recognize and to remove
modified lipoproteins; however, it is now appreciated that they carry out a striking range of …

Structure-function of CD36 and importance of fatty acid signal transduction in fat metabolism

MY Pepino, O Kuda, D Samovski… - Annual review of …, 2014 - annualreviews.org
CD36 (cluster of differentiation 36) is a scavenger receptor that functions in high-affinity
tissue uptake of long-chain fatty acids (FAs) and contributes under excessive fat supply to …

Taste of fat: a sixth taste modality?

P Besnard, P Passilly-Degrace… - Physiological …, 2016 - journals.physiology.org
An attraction for palatable foods rich in lipids is shared by rodents and humans. Over the last
decade, the mechanisms responsible for this specific eating behavior have been actively …

Genetic background of taste perception, taste preferences, and its nutritional implications: a systematic review

J Diószegi, E Llanaj, R Ádány - Frontiers in genetics, 2019 - frontiersin.org
Background: The rise in nutrition-related morbidity and mortality requires public health
intervention programs targeting nutritional behavior. In addition to socio-economical, socio …

Role of the gut in lipid homeostasis

NA Abumrad, NO Davidson - Physiological reviews, 2012 - journals.physiology.org
Intestinal lipid transport plays a central role in fat homeostasis. Here we review the pathways
regulating intestinal absorption and delivery of dietary and biliary lipid substrates, principally …

Food-saliva interactions: Mechanisms and implications

AC Mosca, J Chen - Trends in Food Science & Technology, 2017 - Elsevier
Background Saliva is a complex fluid with multifunctional roles in the oral cavity. Even
though its importance on oral health maintenance has long been recognized, the critical …

Flavor chemistry of virgin olive oil: An overview

A Genovese, N Caporaso, R Sacchi - Applied Sciences, 2021 - mdpi.com
Virgin olive oil (VOO) has unique chemical characteristics among all other vegetable oils
which are of paramount importance for human health. VOO constituents are also …

Multiscale structures of lipids in foods as parameters affecting fatty acid bioavailability and lipid metabolism

MC Michalski, C Genot, C Gayet, C Lopez, F Fine… - Progress in lipid …, 2013 - Elsevier
On a nutritional standpoint, lipids are now being studied beyond their energy content and
fatty acid (FA) profiles. Dietary FA are building blocks of a huge diversity of more complex …