Inflammatory mediators of endothelial dysfunction

E Dri, E Lampas, G Lazaros, E Lazarou, P Theofilis… - Life, 2023 - mdpi.com
Endothelial dysfunction (ED) is characterized by imbalanced vasodilation and
vasoconstriction, elevated reactive oxygen species (ROS), and inflammatory factors, as well …

Two sides of the same coin: Non-alcoholic fatty liver disease and atherosclerosis

B Zhu, H Wu, KS Li, S Eisa-Beygi, B Singh… - Vascular …, 2023 - Elsevier
The prevalence of non-alcoholic fatty liver disease (NAFLD) and atherosclerosis remain
high, which is primarily due to widespread adoption of a western diet and sedentary lifestyle …

Correlation of the Pro-Inflammatory Cytokines IL-1β, IL-6, and TNF-α, Inflammatory Markers, and Tumor Markers with the Diagnosis and Prognosis of Colorectal …

DN Florescu, MV Boldeanu, RE Șerban, LM Florescu… - Life, 2023 - mdpi.com
Colorectal cancer (CRC) remains one of the most important global health problems, being in
the top 3 neoplasms in terms of the number of cases worldwide. Although CRC develops …

[HTML][HTML] LncRNA HOTAIR inhibits miR-19a-3p to alleviate foam cell formation and inflammatory response in atherosclerosis

H Chen, X Li, W Chen, T Wu, S Liu - International Journal of …, 2024 - ncbi.nlm.nih.gov
Background: Atherosclerosis, a chronic inflammatory disease, poses a significant risk for
cardiovascular disorders. Meanwhile, emerging evidence suggests that long noncoding …

Moxonidine Increases Uptake of Oxidised Low-Density Lipoprotein in Cultured Vascular Smooth Muscle Cells and Inhibits Atherosclerosis in Apolipoprotein E …

Y Wang, DT Nguyen, J Anesi, A Alramahi… - International Journal of …, 2023 - mdpi.com
This study aimed to investigate the effect of the sympatholytic drug moxonidine on
atherosclerosis. The effects of moxonidine on oxidised low-density lipoprotein (LDL) uptake …

The Role of Bacterial Extracellular Membrane Nanovesicles in Atherosclerosis: Unraveling a Potential Trigger

KA Lusta, VI Summerhill, VA Khotina… - Current Atherosclerosis …, 2024 - Springer
Abstract Purpose of Review In this review, we explore the intriguing and evolving
connections between bacterial extracellular membrane nanovesicles (BEMNs) and …

Tailoring Treatment in Cardiovascular Diseases: The Role of Targeted Therapies

R Dankar, J Wehbi, MM Refaat - Pharmaceutics, 2024 - mdpi.com
Cardiovascular diseases (CVDs) remain the leading cause of morbidity and mortality around
the globe. To address this public health burden, innovative therapeutic agents are being …

Challenging and target-based shifting strategies for heart failure treatment: An update from the last decades

Y Hattori, K Hattori, K Ishii, M Kobayashi - Biochemical Pharmacology, 2024 - Elsevier
Heart failure (HF) is a major global health problem afflicting millions worldwide. Despite the
significant advances in therapies and prevention, HF still carries very high morbidity and …

The Perspectives of Platelet Proteomics in Health and Disease

PK Chaudhary, S Upadhayaya, S Kim, S Kim - Biomedicines, 2024 - mdpi.com
Cardiovascular thromboembolic diseases and cancer continue to be a leading cause of
death and disability worldwide. Therefore, it is crucial to advance their diagnoses and …

Endothelial Dysfunction in Primary Sjögren's Syndrome: Correlation with Serum Biomarkers of Disease Activity

A Caraba, S Iurciuc, M Nicolin, M Iurciuc - International Journal of …, 2023 - mdpi.com
To assess the relationship between endothelial dysfunction and serum cytokines, anti-SSA
and anti-SSB antibodies, beta-2 microglobulin levels, focus score and EULAR Sjögren's …