Mechanisms of neuronal cell death in ischemic stroke and their therapeutic implications
Ischemic stroke caused by arterial occlusion is the most common type of stroke, which is
among the most frequent causes of disability and death worldwide. Current treatment …
among the most frequent causes of disability and death worldwide. Current treatment …
[PDF][PDF] VEGF in signaling and disease: beyond discovery and development
The discovery of vascular endothelial-derived growth factor (VEGF) has revolutionized our
understanding of vasculogenesis and angiogenesis during development and physiological …
understanding of vasculogenesis and angiogenesis during development and physiological …
Uterine bleeding: how understanding endometrial physiology underpins menstrual health
V Jain, RR Chodankar, JA Maybin… - Nature reviews …, 2022 - nature.com
Menstruation is a physiological process that is typically uncomplicated. However, up to one
third of women globally will be affected by abnormal uterine bleeding (AUB) at some point in …
third of women globally will be affected by abnormal uterine bleeding (AUB) at some point in …
The treatment of impaired wound healing in diabetes: looking among old drugs
SF Spampinato, GI Caruso, R De Pasquale… - Pharmaceuticals, 2020 - mdpi.com
Chronic wounds often occur in patients with diabetes mellitus due to the impairment of
wound healing. This has negative consequences for both the patient and the medical …
wound healing. This has negative consequences for both the patient and the medical …
[HTML][HTML] Physiology of the endometrium and regulation of menstruation
HOD Critchley, JA Maybin… - Physiological …, 2020 - journals.physiology.org
The physiological functions of the uterine endometrium (uterine lining) are preparation for
implantation, maintenance of pregnancy if implantation occurs, and menstruation in the …
implantation, maintenance of pregnancy if implantation occurs, and menstruation in the …
Pathophysiological implications of hypoxia in human diseases
Oxygen is essentially required by most eukaryotic organisms as a scavenger to remove
harmful electron and hydrogen ions or as a critical substrate to ensure the proper execution …
harmful electron and hydrogen ions or as a critical substrate to ensure the proper execution …
Insights into the post-translational modification and its emerging role in shaping the tumor microenvironment
More and more in-depth studies have revealed that the occurrence and development of
tumors depend on gene mutation and tumor heterogeneity. The most important …
tumors depend on gene mutation and tumor heterogeneity. The most important …
[HTML][HTML] Tumor hypoxia: impact on radiation therapy and molecular pathways
BS Sørensen, MR Horsman - Frontiers in oncology, 2020 - frontiersin.org
Tumor hypoxia is a common feature of the microenvironment in solid tumors, primarily due to
an inadequate, and heterogeneous vascular network. It is associated with resistance to …
an inadequate, and heterogeneous vascular network. It is associated with resistance to …
Hypoxia and extracellular vesicles: A review on methods, vesicular cargo and functions
N Bister, C Pistono, B Huremagic… - Journal of …, 2020 - Wiley Online Library
Hypoxia is an essential hallmark of several serious diseases such as cardiovascular and
metabolic disorders and cancer. A decline in the tissue oxygen level induces hypoxic …
metabolic disorders and cancer. A decline in the tissue oxygen level induces hypoxic …
Endothelial–mesenchymal transition in atherosclerosis
C Souilhol, MC Harmsen, PC Evans… - Cardiovascular …, 2018 - academic.oup.com
Atherosclerosis is an inflammatory disease resulting in the hardening and thickening of the
wall of arteries and the formation of plaques, which comprise immune cells, mesenchymal …
wall of arteries and the formation of plaques, which comprise immune cells, mesenchymal …